{"id":"W2020537728","doi":"10.1007/s15010-005-5073-5","title":"Silencing of Bak Ameliorates Apoptosis of Human Proximal Tubular Epithelial Cells by Escherichia coli–Derived Shiga Toxin 2","year":2005,"lang":"en","type":"article","venue":"Infection","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"ca_institutions":"Montreal Children's Hospital","funders":"","keywords":"Gene silencing; Shiga toxin; Apoptosis; Transfection; Biology; Molecular biology; RNA interference; Small interfering RNA; Shiga-like toxin; Programmed cell death; Poly ADP ribose polymerase; Blot; Cell culture; Cell biology; Escherichia coli; Gene; RNA; Polymerase; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000239209,0.0001566406,0.0002262218,0.00005761136,0.00009564906,0.00001268546,0.0001086947,0.000143468,0.00003137691],"category_scores_gemma":[0.0001045306,0.0001553362,0.0001009125,0.0001803343,0.0001503467,0.00001096738,0.0001184941,0.0001188653,0.000004407859],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003213716,"about_ca_system_score_gemma":0.0000555903,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003438311,"about_ca_topic_score_gemma":0.0001003581,"domain_scores_codex":[0.9989045,0.0001088872,0.0003029973,0.0002587435,0.0001895132,0.0002353941],"domain_scores_gemma":[0.9993231,0.00001744787,0.000177096,0.0002169003,0.0002108031,0.00005468467],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005744584,0.0001882747,0.00333785,0.00006925533,0.00008568824,1.204091e-7,0.0001101469,0.000116122,0.9946788,0.0000119308,0.0007601197,0.0005842212],"study_design_scores_gemma":[0.0004400639,0.0007226697,0.003651147,0.00002071181,0.00002321884,3.690885e-7,0.00005401922,0.0001059451,0.992965,0.00001399791,0.001857646,0.0001451779],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984711,0.0002543406,0.0004071919,0.00004857887,0.00007271662,0.0002790331,0.00002835058,0.00001715201,0.0004214792],"genre_scores_gemma":[0.9986641,0.0002713238,0.0005894748,0.00003652288,0.0001966405,0.0000498415,0.00003026778,0.00002131426,0.0001405058],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001713792,"threshold_uncertainty_score":0.6334425,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009644201785108237,"score_gpt":0.264121114570232,"score_spread":0.2544769127851237,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}