{"id":"W2020537728","doi":"10.1007/s15010-005-5073-5","title":"Silencing of Bak Ameliorates Apoptosis of Human Proximal Tubular Epithelial Cells by Escherichia coli–Derived Shiga Toxin 2","year":2005,"lang":"en","type":"article","venue":"Infection","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"ca_institutions":"Montreal Children's Hospital","funders":"","keywords":"Gene silencing; Shiga toxin; Apoptosis; Transfection; Biology; Molecular biology; RNA interference; Small interfering RNA; Shiga-like toxin; Programmed cell death; Poly ADP ribose polymerase; Blot; Cell culture; Cell biology; Escherichia coli; Gene; RNA; Polymerase; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002903955,0.0004424764,0.0006038164,0.0003140261,0.0002869178,0.0004971244,0.0002709659,0.0004368921,0.001496688],"category_scores_gemma":[0.000173253,0.0003087411,0.0005099818,0.0002108048,0.0003566466,0.0003549601,0.0002519743,0.001071177,0.0004352082],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003045692,"about_ca_system_score_gemma":0.0003727478,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007708076,"about_ca_topic_score_gemma":0.0009083559,"domain_scores_codex":[0.999707,0.00006040183,0.00004195008,0.00003809971,0.00005355977,0.00009899482],"domain_scores_gemma":[0.9998062,0.00004789314,0.00003546708,0.00003727468,0.00002602569,0.00004706976],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002839112,0.0000401763,0.00008339416,0.00002840587,0.000006497231,0.00006264092,0.00001968828,0.00003352208,0.9990346,0.00006968653,0.00003026801,0.0003070966],"study_design_scores_gemma":[0.00003746042,0.0003845418,0.001951224,0.000003743222,0.00002104341,0.0002280476,0.0000617364,0.0005835943,0.995728,0.00003747635,0.0009595685,0.000003651813],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962335,0.000972669,0.001605194,0.00016796,0.00005051834,0.00001900627,0.000199276,0.0000833637,0.0006686452],"genre_scores_gemma":[0.9966229,0.0005119588,0.0007071458,0.00004463477,0.00001136371,0.00001582656,0.0003278682,0.00002140975,0.001736874],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001496688,"threshold_uncertainty_score":0.005006969,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009644201785108237,"score_gpt":0.264121114570232,"score_spread":0.2544769127851237,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}