{"id":"W2020545615","doi":"10.1002/stem.1040","title":"Induction of Osteogenesis in Mesenchymal Stem Cells by Activated Monocytes/Macrophages Depends on Oncostatin M Signaling","year":2012,"lang":"en","type":"article","venue":"Stem Cells","topic":"Bone Metabolism and Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":470,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Ligue Contre le Cancer; Institut National de la Santé et de la Recherche Médicale","keywords":"Oncostatin M; Cell biology; Biology; Osteoblast; Osteoimmunology; Bone resorption; Mesenchymal stem cell; Immunology; RANKL; Cytokine; Endocrinology; Receptor; Interleukin 6; Biochemistry; Activator (genetics)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009087681,0.0002067721,0.0001930312,0.0001585413,0.0001208651,0.000199703,0.00006754411,0.0001142085,0.001144233],"category_scores_gemma":[0.00006530608,0.00008688638,0.0002837002,0.0001535271,0.0001268165,0.00008099011,0.0002207873,0.0003050643,0.0003522281],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001419118,"about_ca_system_score_gemma":0.0002502097,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002693232,"about_ca_topic_score_gemma":0.0006306881,"domain_scores_codex":[0.9998575,0.00001681608,0.00001430499,0.00001800407,0.00003880535,0.00005446945],"domain_scores_gemma":[0.9999475,0.000008333541,0.00001310168,0.000006054686,0.000007245674,0.00001763445],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001560216,0.00001897273,0.0005006639,0.00004992404,0.00000360681,0.00007406939,0.00001318396,0.00002832899,0.9968916,0.0001485776,0.00005970232,0.002055534],"study_design_scores_gemma":[0.00003255871,0.0003058434,0.01230199,0.00001004408,0.00001569725,0.0002441505,0.00004724559,0.0005074203,0.9811788,0.00008199445,0.005270478,0.000003857328],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9889392,0.002238941,0.004859002,0.0001230358,0.00004875791,0.00005278668,0.0009059851,0.00008464153,0.002747688],"genre_scores_gemma":[0.9919742,0.001555453,0.003180653,0.0001074056,0.00002016998,0.00007796525,0.001036638,0.000008352026,0.002039111],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001144233,"threshold_uncertainty_score":0.00382781,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01398210718161558,"score_gpt":0.2402610454620187,"score_spread":0.2262789382804031,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}