{"id":"W2020545615","doi":"10.1002/stem.1040","title":"Induction of Osteogenesis in Mesenchymal Stem Cells by Activated Monocytes/Macrophages Depends on Oncostatin M Signaling","year":2012,"lang":"en","type":"article","venue":"Stem Cells","topic":"Bone Metabolism and Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":470,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Ligue Contre le Cancer; Institut National de la Santé et de la Recherche Médicale","keywords":"Oncostatin M; Cell biology; Biology; Osteoblast; Osteoimmunology; Bone resorption; Mesenchymal stem cell; Immunology; RANKL; Cytokine; Endocrinology; Receptor; Interleukin 6; Biochemistry; Activator (genetics)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002092864,0.0002050566,0.0002428964,0.00007996296,0.00004187389,0.00001418045,0.0001351176,0.0001731456,0.00003904261],"category_scores_gemma":[0.000004303413,0.0001924737,0.00009204732,0.0001622012,0.00003962508,0.00001410205,0.00006237595,0.00008474632,0.00002007803],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002081417,"about_ca_system_score_gemma":0.0000479414,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007164331,"about_ca_topic_score_gemma":0.000004809815,"domain_scores_codex":[0.9986893,0.0001754788,0.000311746,0.0002998012,0.0001824024,0.0003412657],"domain_scores_gemma":[0.9993353,0.00003458589,0.0001668912,0.0002763713,0.00004934664,0.000137476],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001980736,0.0002211478,0.001649276,0.00004361816,0.00002960658,0.000001660147,0.0001021487,0.0001478057,0.9857076,0.000006064055,0.0007310301,0.01116197],"study_design_scores_gemma":[0.0006729336,0.0001549313,0.0006773794,0.00002261402,0.00003058875,0.000001197864,0.0005604362,0.000004465716,0.9950665,0.00000187313,0.002608708,0.0001983581],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951472,0.003732876,0.00005750855,0.00001053437,0.0003220306,0.0002074715,0.0001711921,0.00001112319,0.0003400696],"genre_scores_gemma":[0.9987317,0.0001857936,0.0001071157,0.0000532388,0.0001381789,0.00001819831,0.00005749516,0.000031005,0.0006773017],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01096362,"threshold_uncertainty_score":0.7848849,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01398210718161558,"score_gpt":0.2402610454620187,"score_spread":0.2262789382804031,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}