{"id":"W2020572068","doi":"10.1016/s0008-6363(01)00234-6","title":"Signalling in cardiac disease: the molecular deficit at the heart of the problem","year":2001,"lang":"en","type":"letter","venue":"Cardiovascular Research","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Disease; Heart disease; Signalling; Medicine; Cardiology; Internal medicine; Biology; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.005089717,0.0003918109,0.001282375,0.0002120693,0.000531529,0.00004042658,0.0007486233,0.0005959612,0.00006079628],"category_scores_gemma":[0.0003871607,0.0001910291,0.004776234,0.001346733,0.001282621,0.0000285125,0.0007291142,0.006108375,0.00008843045],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000399515,"about_ca_system_score_gemma":0.0007203054,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002657585,"about_ca_topic_score_gemma":0.000006504627,"domain_scores_codex":[0.9900129,0.004709293,0.0004571406,0.0008087907,0.002841012,0.001170839],"domain_scores_gemma":[0.9952433,0.0008692316,0.00007980698,0.003232533,0.0004702491,0.0001048546],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005195615,0.00007756017,0.002536582,0.00159509,0.009637198,0.008571151,0.0002651246,0.01056236,0.007304993,0.0003011566,0.9547538,0.003875388],"study_design_scores_gemma":[0.0005443491,0.00007207224,0.003980575,0.0005311771,0.001052455,0.0003190024,0.00004881314,0.00002571366,0.00138118,0.0004674152,0.9913214,0.0002558588],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.134329,0.2978304,0.00003488884,0.556451,0.0003961636,0.006240355,0.00007479385,0.00004416037,0.004599285],"genre_scores_gemma":[0.7712983,0.01700729,0.00008464536,0.1604698,0.01791296,0.003931005,0.0007081144,0.0007863784,0.02780152],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.6369693,"threshold_uncertainty_score":0.9961846,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03069435117665861,"score_gpt":0.2983267861004695,"score_spread":0.2676324349238109,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}