{"id":"W2020722847","doi":"10.1111/cns.12325","title":"BNIP3 Interacting with LC3 Triggers Excessive Mitophagy in Delayed Neuronal Death in Stroke","year":2014,"lang":"en","type":"article","venue":"CNS Neuroscience & Therapeutics","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":274,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Canadian Institutes of Health Research; Canadian Stroke Network; University of Manitoba; Manitoba Health Research Council","keywords":"Mitophagy; Autophagy; Mitochondrion; Cell biology; Programmed cell death; Apoptosis; Biology; Downregulation and upregulation; Neuroscience; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001336673,0.0003453449,0.0003880944,0.0001876344,0.0002426741,0.0002341117,0.0002000907,0.0003515976,0.002073414],"category_scores_gemma":[0.0001158485,0.0001560371,0.0002485699,0.00018911,0.0002852934,0.0001799123,0.000278453,0.0006515892,0.0004840271],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004017107,"about_ca_system_score_gemma":0.0002379892,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004981122,"about_ca_topic_score_gemma":0.000717556,"domain_scores_codex":[0.9998966,0.00001092984,0.00001281846,0.00001637331,0.00002332345,0.00003982969],"domain_scores_gemma":[0.9999325,0.000008758851,0.00001975404,0.0000061203,0.00000621008,0.00002658197],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006694215,0.00005522358,0.0003370775,0.0000703615,0.00001132254,0.0002364527,0.00001271519,0.00003840626,0.9976859,0.00006419686,0.00008900917,0.0007298967],"study_design_scores_gemma":[0.0001078514,0.0005994829,0.0222229,0.00002081957,0.00005170693,0.001994562,0.00006067245,0.001207306,0.9722644,0.0001853237,0.001276653,0.000008347137],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957217,0.001353656,0.001509735,0.00009712329,0.00003624752,0.00002633678,0.0002509056,0.00005672368,0.0009475439],"genre_scores_gemma":[0.9967065,0.0006776052,0.0009150453,0.00007482626,0.00001103111,0.00007960225,0.0004729147,0.00001191173,0.001050459],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002073414,"threshold_uncertainty_score":0.006936252,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03359464642988452,"score_gpt":0.3127206675272038,"score_spread":0.2791260210973193,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}