{"id":"W2020792117","doi":"10.1016/s1074-5521(01)00038-2","title":"Rapid screening of the aglycone specificity of glycosidases: applications to enzymatic synthesis of oligosaccharides","year":2001,"lang":"en","type":"article","venue":"Chemistry & Biology","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":43,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Networks of Centres of Excellence of Canada; Natural Sciences and Engineering Research Council of Canada","keywords":"Aglycone; Glycoside hydrolase; Glycosidic bond; Chemistry; Enzyme; Substrate (aquarium); Biochemistry; Acceptor; Stereochemistry; Glycoside; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001804428,0.0002378816,0.0006035396,0.00002890297,0.00006812662,0.000005265611,0.0007784495,0.0002706316,0.002108661],"category_scores_gemma":[0.0004963474,0.00019787,0.0002902412,0.0003732203,0.0004612765,0.00002513908,0.00019889,0.0001641707,0.000004059822],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003699262,"about_ca_system_score_gemma":0.00006542505,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006969287,"about_ca_topic_score_gemma":0.000002415023,"domain_scores_codex":[0.9983992,0.00002563003,0.0007665733,0.0003749575,0.0001523775,0.0002812804],"domain_scores_gemma":[0.9975245,0.000636548,0.000534562,0.001038124,0.0001645572,0.0001017224],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007533906,0.000152894,0.003018675,0.0006877651,0.0001004492,8.811764e-7,0.00007917482,0.00001762253,0.9898064,0.00004725753,0.0000579499,0.005955563],"study_design_scores_gemma":[0.0001444343,0.000006884224,0.0001594303,0.0002188758,0.00008914861,0.00002014691,0.0004837471,0.0000330076,0.9958402,0.0001703853,0.002661081,0.0001726735],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9812887,0.0003822459,0.0003621398,0.0001523803,0.00001830532,0.0001151501,0.0003268168,0.00002900929,0.01732528],"genre_scores_gemma":[0.9988011,0.0001247365,0.0004701572,0.00001581515,0.000121855,0.000110107,0.0000270948,0.00001924482,0.0003099144],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0175124,"threshold_uncertainty_score":0.9988036,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02508907040947501,"score_gpt":0.2494652313664186,"score_spread":0.2243761609569436,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}