{"id":"W2020792435","doi":"10.1111/j.1365-2958.2009.07038.x","title":"Forward genetics in <i>Candida albicans</i> that reveals the Arp2/3 complex is required for hyphal formation, but not endocytosis","year":2010,"lang":"en","type":"article","venue":"Molecular Microbiology","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Research in Immunology and Cancer; McGill University; Université de Montréal; Biotechnology Research Institute","funders":"Canadian Institutes of Health Research","keywords":"Biology; Cell biology; Candida albicans; Endocytosis; Mutant; Saccharomyces cerevisiae; Internalization; Genetic screen; Hypha; Actin; Yeast; Genetics; Gene; Microbiology; Cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002502581,0.0006905138,0.0002742106,0.0004814034,0.0002409257,0.00044808,0.0006587464,0.0004143857,0.001624769],"category_scores_gemma":[0.0002125043,0.0003614362,0.0004634108,0.0003209971,0.0003992331,0.0001475953,0.0003912752,0.001129951,0.0008768544],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005397676,"about_ca_system_score_gemma":0.0005341985,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00310563,"about_ca_topic_score_gemma":0.004675989,"domain_scores_codex":[0.9997329,0.00003665961,0.00003261799,0.00004405241,0.0001176573,0.00003607735],"domain_scores_gemma":[0.9997107,0.00008468597,0.00008129232,0.00004684915,0.00003012642,0.00004625629],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005044222,0.00002054037,0.00007817511,0.00001902231,0.000003572422,0.00006050343,0.000007326394,0.00006422511,0.9986248,0.0002018832,0.00005250812,0.0008169735],"study_design_scores_gemma":[0.00001270783,0.00007980562,0.001199782,0.000008457461,0.00001428455,0.0003688711,0.00001375987,0.0008922553,0.9955567,0.00005101854,0.001795627,0.000006879284],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9708426,0.001129861,0.01748975,0.0003430461,0.00009601854,0.0002655524,0.00243709,0.0006863199,0.006709803],"genre_scores_gemma":[0.9567348,0.001148096,0.03018847,0.0002452461,0.0000217002,0.0001575197,0.002452736,0.0004288675,0.008622539],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00310563,"threshold_uncertainty_score":0.006175101,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02820002929297363,"score_gpt":0.2849314736440998,"score_spread":0.2567314443511262,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}