{"id":"W2020846928","doi":"10.1002/hep.26058","title":"Ammonia control and neurocognitive outcome among urea cycle disorder patients treated with glycerol phenylbutyrate","year":2012,"lang":"en","type":"article","venue":"Hepatology","topic":"Metabolism and Genetic Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":96,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; Hospital for Sick Children; National Center for Research Resources; Seattle Children's Research Institute; Children's National Hospital; University of California, Los Angeles; University of Minnesota; Medical College of Wisconsin; Case Western Reserve University; University of Toronto; University of Utah; Children's Hospital of Pittsburgh; National Center for Advancing Translational Sciences; Children's Hospital Colorado; Tufts Medical Center; Nationwide Children's Hospital","keywords":"Urea cycle; Neurocognitive; Phenylbutyrate; Urea; Ammonia; Internal medicine; Glycerol; Chemistry; Medicine; Gastroenterology; Biochemistry; Psychiatry; Cognition; Arginine; Amino acid","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006936986,0.0002340801,0.0002844188,0.00004270592,0.0000858857,0.00001374871,0.00009463036,0.0001634951,0.00002539848],"category_scores_gemma":[0.00004955909,0.0001865044,0.00004628454,0.00006786148,0.0002314659,0.000009346154,0.00005712204,0.00008493114,0.0000182916],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000001911579,"about_ca_system_score_gemma":0.00001667324,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001479195,"about_ca_topic_score_gemma":0.0002660867,"domain_scores_codex":[0.9987637,0.0001284725,0.0002134425,0.0003376435,0.00009185461,0.0004648343],"domain_scores_gemma":[0.9993936,0.00001832666,0.0001021056,0.0002295932,0.00008329936,0.0001730802],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002865117,0.0001574521,0.9957904,0.000009083868,0.00007599363,0.000002036146,0.00004935215,0.000002067678,0.0008002305,0.00003493411,0.0001003749,0.00269163],"study_design_scores_gemma":[0.004149428,0.0003123352,0.985092,0.00000260168,0.0001130154,0.00001230422,0.00004160226,0.0001025093,0.001014549,0.00001580191,0.008876044,0.000267759],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971176,0.0008578046,0.0003882578,0.00006116703,0.0001069935,0.0003654346,0.00005310842,0.0000178472,0.001031765],"genre_scores_gemma":[0.998598,0.0001105464,0.00008597582,0.0007207645,0.00006045233,0.0000736038,0.0001295491,0.00003275436,0.0001883102],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01069828,"threshold_uncertainty_score":0.7605428,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004362432678481151,"score_gpt":0.2130881388999925,"score_spread":0.2087257062215114,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}