{"id":"W2020849247","doi":"10.1038/mt.2008.143","title":"The Targeted Oncolytic Poxvirus JX-594 Demonstrates Antitumoral, Antivascular, and Anti-HBV Activities in Patients With Hepatocellular Carcinoma","year":2008,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":189,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jennerex Biotherapeutics (Canada)","funders":"","keywords":"Oncolytic virus; Hepatocellular carcinoma; Virology; Cancer research; Carcinoma; Medicine; Oncology; Biology; Internal medicine; Virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002885515,0.0003662665,0.0003203483,0.0001153802,0.0003837649,0.00007591813,0.0003639091,0.0001575313,0.00000999965],"category_scores_gemma":[0.00002136375,0.000267036,0.0001149055,0.0002849626,0.00055617,0.00001713561,0.00008708249,0.0002410165,0.000005271378],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000327143,"about_ca_system_score_gemma":0.0002255646,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007281334,"about_ca_topic_score_gemma":0.00005274688,"domain_scores_codex":[0.9977445,0.0003323514,0.0002679577,0.0005853202,0.0004528117,0.0006170615],"domain_scores_gemma":[0.9989511,0.00002716282,0.00009679519,0.0006828037,0.0001131595,0.0001289822],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001971774,0.0002110717,0.4502653,0.000007489512,0.0001472424,0.0001222607,0.00007026675,0.00003549675,0.5452664,0.00001062287,0.00003612738,0.001855899],"study_design_scores_gemma":[0.004157107,0.002867654,0.1629829,0.00001563231,0.00001000016,0.00002577742,0.00006612465,0.000132906,0.8282561,0.0000260075,0.001035986,0.0004237727],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9892968,0.009562558,0.00009825111,0.0001053429,0.00004495898,0.0007784879,0.0000154325,0.00002118913,0.00007696318],"genre_scores_gemma":[0.9964079,0.002914779,0.0001083906,0.0002329828,0.00003873825,0.00006128115,0.00007159232,0.00007926815,0.00008505988],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2872824,"threshold_uncertainty_score":0.9999782,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01138818154942036,"score_gpt":0.2318983847113721,"score_spread":0.2205102031619517,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}