{"id":"W2020849247","doi":"10.1038/mt.2008.143","title":"The Targeted Oncolytic Poxvirus JX-594 Demonstrates Antitumoral, Antivascular, and Anti-HBV Activities in Patients With Hepatocellular Carcinoma","year":2008,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":189,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jennerex Biotherapeutics (Canada)","funders":"","keywords":"Oncolytic virus; Hepatocellular carcinoma; Virology; Cancer research; Carcinoma; Medicine; Oncology; Biology; Internal medicine; Virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002845136,0.0003190825,0.0006591188,0.0001723921,0.0002227491,0.0002838498,0.000118276,0.0002787096,0.0009036337],"category_scores_gemma":[0.000337082,0.0001411254,0.0002339644,0.0001714978,0.0002471412,0.0002506762,0.0001340368,0.0005900436,0.0002502645],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002223585,"about_ca_system_score_gemma":0.0002373269,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004375855,"about_ca_topic_score_gemma":0.0003972093,"domain_scores_codex":[0.9998947,0.00003206081,0.000009591167,0.00001650209,0.00001677343,0.00003035358],"domain_scores_gemma":[0.9998035,0.00006251653,0.0000272921,0.00002365717,0.00001600886,0.00006709002],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.02651056,0.007753332,0.04340374,0.000319109,0.0002120767,0.002941723,0.0006419983,0.001353889,0.8055363,0.0003124959,0.0009862968,0.1100284],"study_design_scores_gemma":[0.009526846,0.287977,0.3827029,0.00004998636,0.0007691286,0.01454927,0.0004553943,0.007981325,0.2809317,0.0004790343,0.01449612,0.00008131093],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980502,0.0006729303,0.0003002352,0.00006641323,0.000007990482,0.00003839116,0.00004824446,0.00002925061,0.0007862758],"genre_scores_gemma":[0.9990197,0.0002246305,0.0001772409,0.00004813903,0.00001163168,0.00002279922,0.0001328528,0.000004572647,0.0003583346],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009036337,"threshold_uncertainty_score":0.003022969,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01138818154942036,"score_gpt":0.2318983847113721,"score_spread":0.2205102031619517,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}