{"id":"W2020887516","doi":"10.1016/j.antiviral.2014.02.005","title":"The beginning of the end: What is the future of interferon therapy for chronic hepatitis C?","year":2014,"lang":"en","type":"article","venue":"Antiviral Research","topic":"Hepatitis C virus research","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto Liver Centre; University of Toronto","funders":"","keywords":"Simeprevir; Ribavirin; Sofosbuvir; Medicine; Interferon; Hepatitis C; Pegylated interferon; Virology; Daclatasvir; Hepatitis C virus; Internal medicine; Pharmacology; Virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004447374,0.0001343957,0.0002834169,0.0001127534,0.0005285582,0.0001052373,0.000895094,0.0001105555,0.00005877441],"category_scores_gemma":[0.0006129413,0.00005841521,0.0002336366,0.0005863573,0.001297925,0.0001774061,0.0003176433,0.0008017949,0.00002178173],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001174699,"about_ca_system_score_gemma":0.0004660579,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009554733,"about_ca_topic_score_gemma":0.001030421,"domain_scores_codex":[0.9965052,0.0008099174,0.0003356649,0.0002641293,0.001430025,0.0006550528],"domain_scores_gemma":[0.9959823,0.002098348,0.0001007543,0.001064404,0.0007071348,0.00004698933],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004948127,0.00007078794,0.02489238,0.0001493072,0.0001175827,0.000001155168,0.001266504,2.844123e-7,0.04525957,0.003498194,0.01164257,0.9126068],"study_design_scores_gemma":[0.002294459,0.004749165,0.05159696,0.0008943851,0.00002238133,0.000004080752,0.00164383,0.003409149,0.4338302,0.00233261,0.4990606,0.0001622038],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9425662,0.01014304,0.00009273861,0.04165648,0.0003385115,0.002047058,0.00002188086,0.00001270287,0.00312144],"genre_scores_gemma":[0.9693418,0.02790794,0.00002568138,0.0002584494,0.0005684881,0.0001273986,0.000004270976,0.00003433975,0.001731674],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9124447,"threshold_uncertainty_score":0.478226,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05609946185193702,"score_gpt":0.4059276083611312,"score_spread":0.3498281465091941,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}