{"id":"W2020887516","doi":"10.1016/j.antiviral.2014.02.005","title":"The beginning of the end: What is the future of interferon therapy for chronic hepatitis C?","year":2014,"lang":"en","type":"article","venue":"Antiviral Research","topic":"Hepatitis C virus research","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto Liver Centre; University of Toronto","funders":"","keywords":"Simeprevir; Ribavirin; Sofosbuvir; Medicine; Interferon; Hepatitis C; Pegylated interferon; Virology; Daclatasvir; Hepatitis C virus; Internal medicine; Pharmacology; Virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01915789,0.0007614953,0.003224903,0.001221608,0.001838457,0.00598573,0.001964835,0.008713555,0.009571099],"category_scores_gemma":[0.02668603,0.000415275,0.001574051,0.001048008,0.005558,0.01631695,0.002169761,0.01067867,0.002549602],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002298902,"about_ca_system_score_gemma":0.008993951,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002599534,"about_ca_topic_score_gemma":0.006717423,"domain_scores_codex":[0.9931049,0.004261867,0.0004809612,0.0004002367,0.001192624,0.000559327],"domain_scores_gemma":[0.9605665,0.02432353,0.002743119,0.001042747,0.006507379,0.004816609],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.003998344,0.0005970127,0.00307005,0.007003226,0.000343116,0.0006658831,0.0008238528,0.0007875606,0.001534793,0.05000386,0.2792474,0.6519249],"study_design_scores_gemma":[0.000667403,0.001404702,0.005132248,0.01460943,0.0004947319,0.0009268443,0.003011266,0.001207909,0.0005526476,0.1091254,0.8625923,0.0002751731],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"commentary","genre_scores_codex":[0.0009263927,0.7273692,0.0005170079,0.2599766,0.00817807,0.00001149362,0.00009755427,0.00003209727,0.002891545],"genre_scores_gemma":[0.03214412,0.7567682,0.00273321,0.1427405,0.06146384,0.00009841748,0.0002195577,0.00005660411,0.003775625],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.01915789,"threshold_uncertainty_score":0.1013179,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05609946185193702,"score_gpt":0.4059276083611312,"score_spread":0.3498281465091941,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}