{"id":"W2020924801","doi":"10.1074/jbc.m611066200","title":"Grb10 and Active Raf-1 Kinase Promote Bad-dependent Cell Survival","year":2007,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"14-3-3 protein interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Biotechnology Research Institute","funders":"","keywords":"Protein kinase B; Pleckstrin homology domain; Cell biology; Signal transducing adaptor protein; Kinase; Biology; Signal transduction; GRB10; Protein kinase A; Cancer research; Insulin receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002011393,0.0004788557,0.0002228171,0.0002660526,0.0001759275,0.0003092218,0.0001964475,0.0002423361,0.001986593],"category_scores_gemma":[0.0001263795,0.000197744,0.0003486369,0.000111407,0.0002427489,0.0002332217,0.0004702772,0.000717895,0.0008525801],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002292298,"about_ca_system_score_gemma":0.0002409802,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003864767,"about_ca_topic_score_gemma":0.0006355025,"domain_scores_codex":[0.9997773,0.00003655015,0.00001540986,0.0000259862,0.0000557604,0.00008908489],"domain_scores_gemma":[0.9998385,0.00003391186,0.00002524075,0.0000196602,0.00001476326,0.00006792733],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007004561,0.000155513,0.0004252833,0.00009872082,0.00001522141,0.0001238782,0.00002820523,0.0001687524,0.9954427,0.0003716208,0.000194344,0.00227534],"study_design_scores_gemma":[0.0001098711,0.001027998,0.007180759,0.00001426162,0.00003182873,0.0007523932,0.00007885889,0.001951943,0.9816274,0.000240678,0.006971971,0.00001198786],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9915683,0.002646304,0.002013725,0.0002479893,0.00009397338,0.00002619143,0.0002645228,0.000141988,0.002997113],"genre_scores_gemma":[0.9940433,0.0008548198,0.0007516176,0.00009115695,0.00001553935,0.00002901722,0.0004902511,0.00001471983,0.003709668],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001986593,"threshold_uncertainty_score":0.006645799,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01406598518441748,"score_gpt":0.2706496180493733,"score_spread":0.2565836328649558,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}