{"id":"W2021031411","doi":"10.1016/j.placenta.2005.05.007","title":"Expression of the Multidrug Resistance P-Glycoprotein, (ABCB1 glycoprotein) in the Human Placenta Decreases with Advancing Gestation","year":2005,"lang":"en","type":"article","venue":"Placenta","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":223,"is_retracted":false,"has_abstract":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital; University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Syncytiotrophoblast; Gestation; Placenta; P-glycoprotein; Fetus; Biology; Messenger RNA; Andrology; Fetal membrane; Multiple drug resistance; Glycoprotein; Immunohistochemistry; Internal medicine; Endocrinology; Pregnancy; Immunology; Molecular biology; Gene; Biochemistry; Drug resistance; Medicine; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004168291,0.0002311443,0.0002960408,0.00008079319,0.000216142,0.00001812165,0.0002801675,0.00008108616,0.00009640714],"category_scores_gemma":[0.00005458981,0.0001206238,0.00009041984,0.0003232073,0.0001054542,0.000181254,0.00002810714,0.0003163952,0.000007111781],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001340956,"about_ca_system_score_gemma":0.0001017736,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001985182,"about_ca_topic_score_gemma":0.006413422,"domain_scores_codex":[0.9980771,0.0001164264,0.0004160405,0.0003352024,0.0006943514,0.0003608684],"domain_scores_gemma":[0.9989012,0.00008617415,0.000238895,0.0006190226,0.0000707949,0.00008394998],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00682008,0.001914269,0.1226572,0.001083307,0.0000603213,0.0001763885,0.01154059,0.0007069288,0.8481816,0.002200626,0.00253281,0.00212583],"study_design_scores_gemma":[0.0089021,0.0002126291,0.1107155,0.004654232,0.0001609401,0.00004793967,0.005717044,0.0001842593,0.8515322,0.0002043161,0.01725405,0.0004147796],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937431,0.0005415438,0.0004958549,0.001793925,0.00005913543,0.001627571,0.00002037901,0.00004276203,0.001675754],"genre_scores_gemma":[0.9925342,0.00005442986,0.005123123,0.0003128499,0.00009524471,0.0001090931,0.00004926665,0.00003412892,0.001687707],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01472124,"threshold_uncertainty_score":0.4918896,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008002039402135081,"score_gpt":0.2442794737632989,"score_spread":0.2362774343611639,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}