{"id":"W2021074825","doi":"10.1534/genetics.114.173856","title":"Replisome Function During Replicative Stress Is Modulated by Histone H3 Lysine 56 Acetylation Through Ctf4","year":2015,"lang":"en","type":"article","venue":"Genetics","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Cancer Research; Institut National Du Cancer","keywords":"Replisome; Biology; Acetylation; DNA replication; Histone; Genetics; Histone H3; Lysine; Cell biology; Eukaryotic DNA replication; DNA; Gene; Amino acid","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001240843,0.0002109009,0.000165824,0.00003099989,0.00008489042,0.00002426725,0.0001785423,0.0002472209,0.00002532723],"category_scores_gemma":[0.00005813449,0.0002284059,0.00008928571,0.0001532866,0.00005701582,0.000009073875,0.0001562137,0.00008893771,0.00003554481],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008057731,"about_ca_system_score_gemma":0.0000521362,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002215275,"about_ca_topic_score_gemma":0.00001116625,"domain_scores_codex":[0.9985142,0.00005756606,0.0002854747,0.0006263134,0.0002437975,0.0002726156],"domain_scores_gemma":[0.9985368,0.000003655386,0.0001819474,0.0009140964,0.0002458977,0.0001175481],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001090157,0.0000698425,0.0003435648,0.00001391883,0.0000833747,0.000001218543,0.0002186873,0.0005570815,0.9885554,0.00002032079,0.00935655,0.0006709641],"study_design_scores_gemma":[0.000799813,0.0004128848,0.0006478429,0.00000980735,0.00005675473,0.000009636775,0.0001214129,0.000588702,0.9740014,0.0004496177,0.02263314,0.0002689975],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9861075,0.002205031,0.01016188,0.0002359109,0.0002442706,0.0002720646,0.00007445191,0.00006752557,0.0006313625],"genre_scores_gemma":[0.9913807,0.0002222433,0.003484001,0.0002250094,0.0002678858,0.00003299976,0.0006421207,0.00005408695,0.003690961],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01455407,"threshold_uncertainty_score":0.9314124,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01668349733881297,"score_gpt":0.269198847323742,"score_spread":0.252515349984929,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}