{"id":"W2021081647","doi":"10.1074/jbc.m109.061523","title":"The Recognition Unit of FIBCD1 Organizes into a Noncovalently Linked Tetrameric Structure and Uses a Hydrophobic Funnel (S1) for Acetyl Group Recognition","year":2009,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research; Lundbeckfonden","keywords":"Ectodomain; Chemistry; Biochemistry; Binding site; Tetramer; Coiled coil; Biophysics; Biology; Stereochemistry; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001232225,0.0003173079,0.0002684084,0.0002498361,0.0002930866,0.0002686188,0.000301307,0.0003655904,0.001439981],"category_scores_gemma":[0.0001664614,0.0001618617,0.0004172181,0.0001463905,0.0001994817,0.0002236875,0.0002934352,0.0002872536,0.0009572451],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005380826,"about_ca_system_score_gemma":0.0001888733,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007182864,"about_ca_topic_score_gemma":0.0008945867,"domain_scores_codex":[0.9998715,0.00001059136,0.0000071673,0.00004994508,0.00002921275,0.00003165358],"domain_scores_gemma":[0.9998798,0.00001340507,0.00002974272,0.00001461499,0.00002330631,0.00003900149],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005871747,0.00001018672,0.001612008,0.00002411919,0.00001018235,0.00007986747,0.00002029148,0.0001084498,0.9949457,0.0001503214,0.00009971245,0.002880488],"study_design_scores_gemma":[0.00001443821,0.0001529306,0.01753807,0.000007951135,0.00001880013,0.0007936755,0.00003620897,0.003116365,0.9741207,0.0001227992,0.004063553,0.00001467211],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9918943,0.0007144485,0.005581366,0.00007716419,0.00001556468,0.00003103805,0.0001289332,0.0001374941,0.00141961],"genre_scores_gemma":[0.9872377,0.0002632154,0.008917085,0.0001087302,0.000008493682,0.00002759674,0.0006338855,0.0000229165,0.002780432],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001439981,"threshold_uncertainty_score":0.004817247,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02030576151295191,"score_gpt":0.2393450117807341,"score_spread":0.2190392502677822,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}