{"id":"W2021087580","doi":"10.1016/j.jcmgh.2015.02.002","title":"Expression of Viral Antigen by the Liver Leads to Chronic Infection Through the Generation of Regulatory T Cells","year":2015,"lang":"en","type":"article","venue":"Cellular and Molecular Gastroenterology and Hepatology","topic":"Animal Virus Infections Studies","field":"Agricultural and Biological Sciences","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"Canadian Institutes of Health Research; Canadian Association for the Study of the Liver; Armand-Frappier Foundation; Natural Sciences and Engineering Research Council of Canada; Fondation Jean-Louis Lévesque; American Liver Foundation","keywords":"Lymphocytic choriomeningitis; Biology; Immune system; Immunology; Immune tolerance; T cell; CD8; Chronic infection; Virus; Virology; Antigen; Regulatory T cell; IL-2 receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002264264,0.0003510393,0.0001639067,0.0001176603,0.0001004411,0.0002664819,0.0001231493,0.0001727579,0.001234124],"category_scores_gemma":[0.0001153725,0.000122511,0.0001697566,0.00005900929,0.0003354684,0.0001292547,0.0001645884,0.0005035659,0.0002906487],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001765991,"about_ca_system_score_gemma":0.0001358762,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000117078,"about_ca_topic_score_gemma":0.0001963119,"domain_scores_codex":[0.9998629,0.00002817745,0.00001193881,0.00002954681,0.00002415101,0.00004323437],"domain_scores_gemma":[0.999842,0.00002734516,0.00005939089,0.00002514934,0.00001523429,0.00003079781],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001784669,0.00003627864,0.0009070017,0.00003320054,0.00000382135,0.00008556627,0.00002014289,0.00004205195,0.9968637,0.0001042162,0.00002566183,0.001699832],"study_design_scores_gemma":[0.0001300071,0.002661398,0.01473052,0.00003226241,0.00005554041,0.001302983,0.00008950993,0.001501478,0.9755321,0.0002543232,0.003700765,0.000009098477],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958844,0.0009549348,0.002078343,0.00004646873,0.00001904198,0.00001798795,0.00003806132,0.0000803506,0.0008805124],"genre_scores_gemma":[0.9974989,0.0003748972,0.0007898819,0.00003305401,0.00001703051,0.00002225268,0.00007476636,0.00001090578,0.001178248],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001234124,"threshold_uncertainty_score":0.004128516,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02407751283800632,"score_gpt":0.2233213147469778,"score_spread":0.1992438019089715,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}