{"id":"W2021087580","doi":"10.1016/j.jcmgh.2015.02.002","title":"Expression of Viral Antigen by the Liver Leads to Chronic Infection Through the Generation of Regulatory T Cells","year":2015,"lang":"en","type":"article","venue":"Cellular and Molecular Gastroenterology and Hepatology","topic":"Animal Virus Infections Studies","field":"Agricultural and Biological Sciences","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"Canadian Institutes of Health Research; Canadian Association for the Study of the Liver; Armand-Frappier Foundation; Natural Sciences and Engineering Research Council of Canada; Fondation Jean-Louis Lévesque; American Liver Foundation","keywords":"Lymphocytic choriomeningitis; Biology; Immune system; Immunology; Immune tolerance; T cell; CD8; Chronic infection; Virus; Virology; Antigen; Regulatory T cell; IL-2 receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001634343,0.0000916183,0.0001619663,0.000009023018,0.0001507816,0.000007026926,0.00007584021,0.00008339795,0.0000106427],"category_scores_gemma":[0.00001265145,0.00003414802,0.00004125216,0.00005025098,0.0003602493,0.00004574703,0.0001227459,0.00007974372,0.000001448569],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009397068,"about_ca_system_score_gemma":0.000005281166,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002020356,"about_ca_topic_score_gemma":0.000353452,"domain_scores_codex":[0.9992349,0.000223089,0.0001591057,0.0001675233,0.00006844039,0.0001469436],"domain_scores_gemma":[0.9997403,0.00002545505,0.00008675265,0.00006158968,0.00005350834,0.00003241221],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005935815,0.00002742346,0.05006991,0.000004297243,0.00001486219,0.000001295121,0.0001652776,0.00001468387,0.9477541,0.0002319025,0.001114316,0.0005425932],"study_design_scores_gemma":[0.0002829528,0.002202485,0.0280473,0.000008076125,0.00004855705,0.00003886985,0.00009603194,0.0001586108,0.9610516,0.0001630563,0.007826181,0.00007626451],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949889,0.002167661,0.001932455,0.0005996317,0.00009184745,0.0001572958,0.000007419257,0.000005618757,0.00004921874],"genre_scores_gemma":[0.9991019,0.000392402,0.00003709265,0.0003830733,0.00004480675,0.00001171127,0.000009056512,9.836401e-7,0.00001890785],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02202261,"threshold_uncertainty_score":0.1392516,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02407751283800632,"score_gpt":0.2233213147469778,"score_spread":0.1992438019089715,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}