{"id":"W2021100286","doi":"10.1006/mgme.2001.3248","title":"A Mutant GTPase Affects the Efficiency of Cholesterol Transfer from Cells to Lipoprotein Acceptors","year":2001,"lang":"en","type":"article","venue":"Molecular Genetics and Metabolism","topic":"Cancer, Lipids, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Simon Fraser University","funders":"","keywords":"Cholesterol; ABCA1; Cancer; Hormone; Lipoprotein; Sterol; Internal medicine; Chemistry; Biology; Endocrinology; Biochemistry; Medicine; Transporter; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003708001,0.0007122681,0.0006944779,0.0007102171,0.0005273568,0.0008536601,0.0008503817,0.001549553,0.002440086],"category_scores_gemma":[0.0007714748,0.0004226578,0.000591677,0.0005884615,0.00118778,0.0003795048,0.0003884716,0.001378407,0.0006895711],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00101447,"about_ca_system_score_gemma":0.0005674996,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002316872,"about_ca_topic_score_gemma":0.00108847,"domain_scores_codex":[0.9995962,0.000112116,0.00006378772,0.00006985749,0.0000906117,0.00006755972],"domain_scores_gemma":[0.9990978,0.0003684074,0.0001340817,0.0001524794,0.00005129815,0.0001958214],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001106036,0.0001659534,0.0002787478,0.00003515983,0.00003141591,0.0003011215,0.000036454,0.000620749,0.9940216,0.001944974,0.0001634456,0.001294362],"study_design_scores_gemma":[0.0001507401,0.0002418147,0.001371787,0.00001515652,0.00005208541,0.0007883555,0.00004195114,0.007149516,0.9873872,0.0004632822,0.002311226,0.00002674459],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964038,0.0003623018,0.001365767,0.0002594904,0.00008164761,0.00001995163,0.0002975359,0.000153405,0.001056173],"genre_scores_gemma":[0.9968924,0.0002370046,0.001356237,0.00006380469,0.00001786477,0.00002231506,0.0002546819,0.0001017448,0.001054157],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002440086,"threshold_uncertainty_score":0.008162916,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005643967941934255,"score_gpt":0.2189259327547024,"score_spread":0.2132819648127681,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}