{"id":"W2021103101","doi":"10.1021/jo0622532","title":"Thiopyran Route to Polypropionates:  Exploiting and Overcoming Double Stereodifferentiation and Mutual Kinetic Enantioselection in Aldol Couplings of Chiral Fragments","year":2007,"lang":"en","type":"article","venue":"The Journal of Organic Chemistry","topic":"Synthetic Organic Chemistry Methods","field":"Chemistry","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Diastereomer; Aldol reaction; Adduct; Chemistry; Enantiomer; Stereochemistry; Organic chemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001905517,0.0005287005,0.000183447,0.0002938961,0.0001561962,0.0002925586,0.0003093341,0.0002144358,0.001210135],"category_scores_gemma":[0.0001761742,0.0002509579,0.0001849594,0.0002142492,0.0002523866,0.0004791858,0.0003872965,0.0005951863,0.0008264399],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001589078,"about_ca_system_score_gemma":0.0002549991,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002150384,"about_ca_topic_score_gemma":0.0005607709,"domain_scores_codex":[0.9998944,0.00001840118,0.00001023082,0.00002076771,0.00002954904,0.00002667711],"domain_scores_gemma":[0.999874,0.00001696711,0.00003862283,0.00002735667,0.00001471094,0.00002834946],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009730639,0.00003756501,0.0001417598,0.00009954083,0.00001444757,0.0005084897,0.00009425333,0.0004503923,0.9835123,0.002559899,0.0001498996,0.01233408],"study_design_scores_gemma":[0.00001350224,0.0002700135,0.0002736542,0.000004089297,0.00001091715,0.000495227,0.00002070108,0.0005557433,0.9909503,0.0002857462,0.007113287,0.000006979985],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9081863,0.002892403,0.07140341,0.0003621689,0.0001752009,0.000166744,0.0004533376,0.0004407597,0.01591968],"genre_scores_gemma":[0.9637804,0.002366001,0.02419179,0.00008318468,0.0000379841,0.00005740671,0.0003164016,0.00007091264,0.009095817],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001210135,"threshold_uncertainty_score":0.004048288,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0134407625034591,"score_gpt":0.2616596009965041,"score_spread":0.248218838493045,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}