{"id":"W2021105398","doi":"10.1021/bc060302b","title":"Binding of Streptavidin with Biotinylated Thermosensitive Nanospheres Based on Poly(<i>N,N</i>-diethylacrylamide-<i>co</i>-2-hydroxyethyl methacrylate)","year":2007,"lang":"en","type":"article","venue":"Bioconjugate Chemistry","topic":"Biotin and Related Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Biotinylation; Streptavidin; Chemistry; 2-Hydroxyethyl Methacrylate; Methacrylate; Conjugate; Copolymer; Bovine serum albumin; Polymer; Polymer chemistry; Biotin; Conjugated system; Chemical engineering; Biophysics; Chromatography; Organic chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005331224,0.0005305102,0.0004509284,0.00006046422,0.0001839605,0.00002417743,0.0002907662,0.0007090592,0.00008250945],"category_scores_gemma":[0.00009516826,0.00041912,0.0002280091,0.0003302233,0.0005584883,0.000005681387,0.00009309646,0.0003893565,0.00001713693],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000461835,"about_ca_system_score_gemma":0.0001276358,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004426136,"about_ca_topic_score_gemma":0.00001155284,"domain_scores_codex":[0.9975896,0.00006423949,0.0005369182,0.0007899662,0.0003587505,0.0006605627],"domain_scores_gemma":[0.9984946,0.00009070318,0.0003771533,0.0006371874,0.0002037551,0.0001965669],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009539334,0.000195679,0.001927844,0.0001268161,0.0003335076,0.00004760651,0.000070703,0.00006489361,0.9943549,0.000008975449,0.0004447846,0.001470344],"study_design_scores_gemma":[0.001590919,0.0005176463,0.0008430926,0.0001969815,0.00007027542,0.0000200092,0.0005130764,0.00005484296,0.9929656,0.000006074478,0.002669004,0.0005524167],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9812248,0.001536182,0.0002477446,0.0001349067,0.0001099362,0.0003073544,0.0001076921,0.0000740312,0.01625736],"genre_scores_gemma":[0.9970427,0.0002354467,0.0009288632,0.0002194245,0.0001775851,0.000007401911,0.0001762592,0.00008183782,0.001130546],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01581785,"threshold_uncertainty_score":0.9998261,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006338354512668756,"score_gpt":0.2395432878741982,"score_spread":0.2332049333615295,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}