{"id":"W2021117030","doi":"10.1002/pros.20420","title":"Differential regulation of IGFBP-3 by the androgen receptor in the lineage-related androgen-dependent LNCaP and androgen-independent C4-2 prostate cancer models","year":2006,"lang":"en","type":"article","venue":"The Prostate","topic":"Growth Hormone and Insulin-like Growth Factors","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Vancouver General Hospital","funders":"","keywords":"LNCaP; Androgen receptor; Prostate cancer; Androgen; Endocrinology; Internal medicine; Cancer research; Biology; Medicine; Cancer; Hormone","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007527028,0.0003737186,0.0004715118,0.0001130393,0.0002736712,0.00007784716,0.0003078015,0.0001752423,0.00009976752],"category_scores_gemma":[0.00002364934,0.000186776,0.0001335276,0.0004303709,0.0003205329,0.000223042,0.000122422,0.0005346597,0.000009336796],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008436157,"about_ca_system_score_gemma":0.000102719,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001695769,"about_ca_topic_score_gemma":0.000225602,"domain_scores_codex":[0.9971212,0.0002878824,0.0008543388,0.0004583336,0.0007494155,0.0005289021],"domain_scores_gemma":[0.9986715,0.0001160251,0.0003755193,0.000586485,0.0001570382,0.00009347458],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0100757,0.003400298,0.2125966,0.000954778,0.00180163,0.000112773,0.075619,0.004213309,0.6208417,0.005307452,0.02511605,0.03996065],"study_design_scores_gemma":[0.02668215,0.002079308,0.1380908,0.0006834737,0.001788633,0.0004947258,0.004942085,0.03490389,0.7621633,0.01628122,0.01010352,0.001786851],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9890665,0.004693489,0.0000457287,0.002765861,0.0001703589,0.002406375,0.0002893587,0.00004741521,0.0005148876],"genre_scores_gemma":[0.9961143,0.001540581,0.00001926352,0.0002080176,0.0001025772,0.0002060432,0.0002609798,0.00005408755,0.00149412],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1413216,"threshold_uncertainty_score":0.7616503,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01094191152143701,"score_gpt":0.2313120417033253,"score_spread":0.2203701301818883,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}