{"id":"W2021132129","doi":"10.1371/journal.pone.0012922","title":"Microarray Analysis of Gene Expression by Skeletal Muscle of Three Mouse Models of Kennedy Disease/Spinal Bulbar Muscular Atrophy","year":2010,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute of Neurological Disorders and Stroke; National Institutes of Health","keywords":"Spinal muscular atrophy; Skeletal muscle; Microarray analysis techniques; Pathology; Progressive muscular atrophy; Gene expression; Muscle atrophy; Atrophy; Medicine; Biology; Neuromuscular disease; Gene expression profiling; Gene; Amyotrophic lateral sclerosis; Anatomy; Disease; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003483944,0.000498973,0.0005499379,0.001042442,0.0003612035,0.0004536929,0.0002767787,0.0004855327,0.001005491],"category_scores_gemma":[0.0002005633,0.0002539774,0.0007191395,0.0009387217,0.0003044333,0.0001365018,0.0002352562,0.000696675,0.0003349411],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003103722,"about_ca_system_score_gemma":0.0002169322,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008048275,"about_ca_topic_score_gemma":0.002280634,"domain_scores_codex":[0.999458,0.00006377513,0.00005915416,0.0001451724,0.0001702764,0.0001036973],"domain_scores_gemma":[0.9996544,0.00008570318,0.00008457676,0.00003055211,0.00008607151,0.00005863771],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001199427,0.00001939571,0.0007164016,0.00003893992,0.00001503582,0.00001230124,0.00001551381,0.00003594912,0.9983652,0.0000168218,0.00003915221,0.0006052939],"study_design_scores_gemma":[0.00005001872,0.001301945,0.1620884,0.00002514622,0.0003012656,0.0004640764,0.0001736283,0.001893443,0.8303017,0.0001288509,0.003223971,0.0000475404],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9774613,0.001287144,0.01156826,0.000154675,0.00006423234,0.0001907568,0.007244818,0.0002303517,0.001798398],"genre_scores_gemma":[0.9201443,0.002456611,0.04442464,0.000551024,0.00006648376,0.001876289,0.02359103,0.0001309324,0.006758589],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001042442,"threshold_uncertainty_score":0.003363729,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03447223949826123,"score_gpt":0.2329333236826193,"score_spread":0.198461084184358,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}