{"id":"W2021156751","doi":"10.1016/j.ydbio.2010.05.204","title":"Gastrulation defects lead to embryonic lethality in porcupine homolog mutant mouse embryos","year":2010,"lang":"en","type":"article","venue":"Developmental Biology","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Gastrulation; Biology; Lethality; Mutant; Porcupine; Embryo; Embryonic stem cell; Cell biology; Embryogenesis; Genetics; Gene; Ecology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004563459,0.0002154394,0.0002169063,0.0001720636,0.00007586772,0.00001528338,0.0003268686,0.0003320554,0.0000826563],"category_scores_gemma":[0.0002089685,0.0002080404,0.00005707091,0.0002150431,0.000110044,0.000005399776,0.0003687499,0.0002955076,0.0002204305],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006921731,"about_ca_system_score_gemma":0.0002022244,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008996043,"about_ca_topic_score_gemma":0.001345186,"domain_scores_codex":[0.9982679,0.0001298358,0.0002961781,0.0006113778,0.0001174058,0.0005772519],"domain_scores_gemma":[0.9994144,0.00002174484,0.00005944332,0.0002915123,0.00006229035,0.0001505849],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009873816,0.0000679733,0.07996548,0.00001041588,0.00001711052,0.00001540078,0.00003478331,0.000008328379,0.9177971,0.00006702499,0.0002201053,0.001697546],"study_design_scores_gemma":[0.0006799753,0.0002167976,0.09538688,0.000005848329,0.000002369295,0.0001093422,0.0000449082,0.00002243808,0.8940563,0.00006125956,0.009128666,0.0002852612],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975218,0.00004558881,0.0002743693,0.0002942307,0.0002681304,0.0004232835,0.00003510958,0.00002177476,0.001115706],"genre_scores_gemma":[0.9952577,0.00002662483,0.002761676,0.0003774829,0.00008560067,0.00006856323,0.0005542745,0.00002305226,0.0008450105],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02374084,"threshold_uncertainty_score":0.8483639,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01296518908263206,"score_gpt":0.2761691498200662,"score_spread":0.2632039607374342,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}