{"id":"W2021184083","doi":"10.1371/journal.pone.0108476","title":"Adenosine Deaminase Acting on RNA-1 (ADAR1) Inhibits HIV-1 Replication in Human Alveolar Macrophages","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"RNA regulation and disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Institute on Drug Abuse; National Heart, Lung, and Blood Institute; Center for AIDS Research, University of Washington; National Institutes of Health; York University","keywords":"Adenosine deaminase; Viral replication; Biology; Virology; In vitro; Molecular biology; Virus; Adenosine; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002000487,0.0002125961,0.0002627281,0.0001211594,0.0001268913,0.0002297399,0.0001389418,0.0001735951,0.0007622931],"category_scores_gemma":[0.0001022602,0.0001133847,0.0002038782,0.00008267262,0.0001277049,0.00008558766,0.0001176709,0.0003804883,0.0003000466],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001215888,"about_ca_system_score_gemma":0.0001438513,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003923925,"about_ca_topic_score_gemma":0.0007751848,"domain_scores_codex":[0.9998753,0.00003393265,0.00001354816,0.00002489228,0.00002444418,0.00002780289],"domain_scores_gemma":[0.9999398,0.00001991437,0.00001033337,0.000009928864,0.00000750424,0.00001251523],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001751382,0.00008355291,0.0001542252,0.00002805885,0.000004851355,0.00001795345,0.00001040754,0.00005930458,0.9979578,0.00002037921,0.00003665642,0.001451612],"study_design_scores_gemma":[0.00004596319,0.001722648,0.003643145,0.000006597464,0.0000167969,0.0001422453,0.00002149256,0.0007473044,0.9924907,0.00002304595,0.001137298,0.000002864642],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995981,0.002210217,0.0006838173,0.00007845468,0.00002409161,0.00001888354,0.0001423198,0.00003504911,0.000826237],"genre_scores_gemma":[0.9960482,0.001022279,0.001259641,0.00004572939,0.00001358313,0.00003013744,0.0002602517,0.000009366857,0.001310936],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007622931,"threshold_uncertainty_score":0.002550066,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02206602157683899,"score_gpt":0.2528626633046452,"score_spread":0.2307966417278063,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}