{"id":"W2021200400","doi":"10.1182/blood-2002-02-0599","title":"Expression of a human β-globin transgene in erythroid cells derived from retrovirally transduced transplantable human fetal liver and cord blood cells","year":2002,"lang":"en","type":"article","venue":"Blood","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Terry Fox Research Institute","funders":"National Heart, Lung, and Blood Institute","keywords":"Biology; Haematopoiesis; Stem cell; Molecular biology; Cord blood; Viral vector; Genetic enhancement; CD34; Transgene; Transplantation; Transduction (biophysics); Cell biology; Immunology; Gene; Genetics; Medicine; Recombinant DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001635047,0.0002768867,0.0003601837,0.00009803561,0.0001069186,0.00002329741,0.0003095925,0.0002661635,0.0003119557],"category_scores_gemma":[0.000002641028,0.0002846422,0.0001311452,0.0001200495,0.0001569087,0.00001079628,0.00003393093,0.0002020148,0.000005088447],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006893654,"about_ca_system_score_gemma":0.00002642828,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000227506,"about_ca_topic_score_gemma":0.000984718,"domain_scores_codex":[0.9981437,0.0001931598,0.0004021727,0.0005862788,0.000252512,0.0004222143],"domain_scores_gemma":[0.9992917,0.0000171281,0.0000842018,0.0004310995,0.00004118426,0.0001347227],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006711712,0.001114469,0.0006727884,0.0000725945,0.00009778573,0.00004918603,0.000530719,0.000008034134,0.9964188,8.800071e-7,0.00003717489,0.0003264069],"study_design_scores_gemma":[0.007470279,0.004329281,0.000977669,0.00007046264,0.000108533,0.000007919013,0.00004621093,0.00001326964,0.9866102,0.00001905212,0.00004180116,0.0003053339],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959354,0.00310171,0.0000420917,0.00001463026,0.00002645361,0.0003958103,0.0002266765,0.00001563979,0.0002416226],"genre_scores_gemma":[0.9975096,0.001625211,0.0003475845,0.00004422021,0.00008229204,0.00002493955,0.0001387035,0.00004978542,0.0001776877],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009808603,"threshold_uncertainty_score":0.9999606,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01852907527038963,"score_gpt":0.2480658505446592,"score_spread":0.2295367752742696,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}