{"id":"W2021200400","doi":"10.1182/blood-2002-02-0599","title":"Expression of a human β-globin transgene in erythroid cells derived from retrovirally transduced transplantable human fetal liver and cord blood cells","year":2002,"lang":"en","type":"article","venue":"Blood","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Terry Fox Research Institute","funders":"National Heart, Lung, and Blood Institute","keywords":"Biology; Haematopoiesis; Stem cell; Molecular biology; Cord blood; Viral vector; Genetic enhancement; CD34; Transgene; Transplantation; Transduction (biophysics); Cell biology; Immunology; Gene; Genetics; Medicine; Recombinant DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002700448,0.000253806,0.0001815517,0.0001997962,0.0001004651,0.0003257291,0.0001570202,0.0002392323,0.0007552444],"category_scores_gemma":[0.0001630869,0.0001387722,0.0001519633,0.0001586845,0.0001977523,0.000135355,0.0001836877,0.0005105537,0.0005105083],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000256225,"about_ca_system_score_gemma":0.000263399,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006375557,"about_ca_topic_score_gemma":0.0005712389,"domain_scores_codex":[0.9998708,0.00002141729,0.00001859688,0.0000276864,0.00004241785,0.00001911853],"domain_scores_gemma":[0.9998922,0.00001871769,0.00002651278,0.00001970452,0.00001857232,0.00002425233],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001651975,0.000005970793,0.0001056202,0.00001216117,0.000001651441,0.00003155632,0.00001496659,0.00002691962,0.9982672,0.00008247889,0.00001683197,0.001418074],"study_design_scores_gemma":[0.00000819587,0.0001675569,0.001924021,0.000008079839,0.00001012147,0.0004742352,0.00001355235,0.0005335546,0.993494,0.00003592562,0.003328246,0.000002638847],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9657847,0.002222938,0.02861411,0.0000947475,0.0000460315,0.0001868086,0.0005409205,0.0002503755,0.002259326],"genre_scores_gemma":[0.9740285,0.001816252,0.01700624,0.00007412758,0.00001611362,0.00009553418,0.001664753,0.00007328096,0.00522523],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007552444,"threshold_uncertainty_score":0.002526581,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01852907527038963,"score_gpt":0.2480658505446592,"score_spread":0.2295367752742696,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}