{"id":"W2021206196","doi":"10.1021/bi010504p","title":"Structural Analyses of Nucleotide Binding to an Aminoglycoside Phosphotransferase<sup>,</sup>","year":2001,"lang":"en","type":"article","venue":"Biochemistry","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":104,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research; Promotion and Mutual Aid Corporation for Private Schools of Japan","keywords":"Nucleotide; Binding site; Aminoglycoside; Phosphotransferase; Kinase; Biology; Biochemistry; Enzyme; Stereochemistry; Chemistry; Antibiotics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007701776,0.0003170551,0.0002118304,0.0000835138,0.0002094089,0.0002422832,0.000397375,0.0002264521,0.0007253488],"category_scores_gemma":[0.0002288339,0.0001390248,0.0003175557,0.0001470904,0.0001501269,0.0001556877,0.0001447711,0.0005307576,0.0002223322],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006571208,"about_ca_system_score_gemma":0.0002825551,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00422276,"about_ca_topic_score_gemma":0.003988497,"domain_scores_codex":[0.9999324,0.000008281743,0.000003211783,0.0000123295,0.00003057192,0.0000132719],"domain_scores_gemma":[0.9999206,0.00001431688,0.00002320528,0.00000503282,0.00001625157,0.00002052356],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003925051,0.00007823151,0.00326353,0.0001738544,0.00003388075,0.0005122815,0.0001113325,0.003506665,0.9862916,0.0005912294,0.0003694815,0.00467552],"study_design_scores_gemma":[0.0001071951,0.000769978,0.07589157,0.00005201083,0.0001575198,0.001829553,0.0004153767,0.05352913,0.8518912,0.0005082435,0.01479294,0.00005533546],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975901,0.0005202455,0.0007004,0.00006130215,0.000009727588,0.000007022988,0.0001904897,0.00003268285,0.0008880612],"genre_scores_gemma":[0.9946929,0.0005366072,0.002203845,0.00004754639,0.000004979334,0.000009779307,0.001623435,0.00002304191,0.0008579077],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00422276,"threshold_uncertainty_score":0.008396327,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02669087512491389,"score_gpt":0.2909246510093919,"score_spread":0.2642337758844779,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}