{"id":"W2021258728","doi":"10.1371/journal.pone.0019174","title":"Ascl1/Mash1 Is a Novel Target of Gli2 during Gli2-Induced Neurogenesis in P19 EC Cells","year":2011,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Hedgehog Signaling Pathway Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Neurogenesis; GLI2; NeuroD; Biology; Gliogenesis; Sonic hedgehog; Cell biology; GLI3; Hedgehog signaling pathway; Transcription factor; Stem cell; Cancer research; Signal transduction; Progenitor cell; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001201149,0.0001886105,0.0003027593,0.00007698918,0.00004311846,0.000005251693,0.0002246909,0.0001425897,0.00003501246],"category_scores_gemma":[0.00009078869,0.0001991351,0.00008923566,0.0001352914,0.00005044341,0.000003689157,0.000189726,0.00009351307,0.00001825907],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001338272,"about_ca_system_score_gemma":0.00004805915,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007905035,"about_ca_topic_score_gemma":0.00002642125,"domain_scores_codex":[0.9987651,0.00003765072,0.0003124591,0.0003939144,0.000185801,0.0003050911],"domain_scores_gemma":[0.999302,0.00001124188,0.0001119482,0.0003970352,0.0001089655,0.00006877557],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007145346,0.000989511,0.01304992,0.0001166407,0.0002316699,0.000008244151,0.0005541582,0.000003417385,0.984935,0.000003789474,0.00001398288,0.00002213715],"study_design_scores_gemma":[0.0006064481,0.0002046624,0.01096295,0.00005443263,0.0000526629,0.000001427993,0.00005577845,0.00002481318,0.9877896,0.00001012852,0.00003976547,0.0001972958],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986981,0.0003269087,0.00003353516,0.0000314457,0.00004664683,0.0002052548,0.0000617847,0.00001657091,0.0005797406],"genre_scores_gemma":[0.9966502,0.00008208745,0.002786922,0.0001135408,0.0000868116,0.00002939183,0.000008391367,0.00003889603,0.0002038219],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002854559,"threshold_uncertainty_score":0.8120493,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07946171755046051,"score_gpt":0.2165541779498502,"score_spread":0.1370924603993897,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}