{"id":"W2021318962","doi":"10.1089/ten.tea.2010.0593","title":"Three-Dimensional Topography of Synthetic Scaffolds Induces Elastin Synthesis by Human Coronary Artery Smooth Muscle Cells","year":2011,"lang":"en","type":"article","venue":"Tissue Engineering Part A","topic":"Connective tissue disorders research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Heart and Stroke Foundation of Canada","keywords":"Elastin; Vascular smooth muscle; Scaffold; Calponin; Cell biology; Downregulation and upregulation; Chemistry; Tissue engineering; Cell culture; Smooth muscle; Actin; Pathology; Biology; Biomedical engineering; Gene; Biochemistry; Endocrinology; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001133254,0.000191839,0.0001585877,0.0001231383,0.00007500964,0.0002207431,0.00007142827,0.0001804238,0.0005530179],"category_scores_gemma":[0.00009585584,0.0001613281,0.0002147057,0.0001021478,0.0001007999,0.00007901807,0.0001633088,0.0002568274,0.0001596784],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000120984,"about_ca_system_score_gemma":0.00008335157,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000488974,"about_ca_topic_score_gemma":0.0009019626,"domain_scores_codex":[0.9998984,0.00001341857,0.000009359102,0.00001998344,0.00002688006,0.00003177469],"domain_scores_gemma":[0.999928,0.00002062087,0.00001773889,0.000009705761,0.000007344663,0.00001656105],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003429334,0.00001455214,0.0001276163,0.00001053363,0.000001768787,0.00002714097,0.00001934815,0.000036612,0.9993508,0.00001018582,0.000008028595,0.0003589949],"study_design_scores_gemma":[0.00001367715,0.000466726,0.01037483,0.000004154737,0.00001256907,0.0001045291,0.00005368895,0.001267407,0.9868274,0.00001918983,0.0008509489,0.00000493176],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985635,0.0003124958,0.0005306886,0.00002041829,0.00000921461,0.00001075938,0.00007936875,0.0000153439,0.0004583265],"genre_scores_gemma":[0.9976514,0.0002631852,0.001071752,0.000030763,0.00000657343,0.00001896389,0.0002134657,0.00000554611,0.0007383017],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005530179,"threshold_uncertainty_score":0.001850009,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01777432202116783,"score_gpt":0.2337609224582216,"score_spread":0.2159866004370537,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}