{"id":"W2021343145","doi":"10.1016/j.bbrc.2008.11.086","title":"The PINK1–Parkin pathway is involved in the regulation of mitochondrial remodeling process","year":2008,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":179,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Ministry of Education, Science and Technology; Centre National de la Recherche Scientifique; Korea Science and Engineering Foundation; University of Toronto; Institut National de la Santé et de la Recherche Médicale; Mesothelioma Applied Research Foundation","keywords":"PINK1; Parkin; Mitochondrial fission; mitochondrial fusion; Mitochondrion; Cell biology; Mitophagy; MFN2; Biology; DNAJA3; Mitochondrial DNA; Parkinson's disease; Genetics; Autophagy; Apoptosis; Gene; Medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003102237,0.0003467172,0.0003103796,0.0003114954,0.0004835224,0.0006689041,0.0002435812,0.0003334507,0.001097047],"category_scores_gemma":[0.0002863898,0.0002019755,0.0001588746,0.0002249048,0.0003332095,0.0008300961,0.0004440188,0.0005476633,0.0004059029],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006724051,"about_ca_system_score_gemma":0.0002890812,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000410847,"about_ca_topic_score_gemma":0.0003830538,"domain_scores_codex":[0.9998292,0.00003801972,0.00001157799,0.00004575691,0.00003958175,0.00003584357],"domain_scores_gemma":[0.9998116,0.00002127459,0.00006725147,0.00001210653,0.00003598772,0.00005184293],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008474521,0.00004640044,0.001560412,0.0002638779,0.00002764052,0.0005021639,0.00009165717,0.0003683155,0.9845541,0.002218385,0.0003952521,0.009124242],"study_design_scores_gemma":[0.0001068724,0.0002764009,0.0480478,0.00003388953,0.0000657506,0.002333384,0.0001766439,0.005052459,0.9272367,0.004083418,0.01255061,0.00003609263],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9483166,0.02719464,0.01726275,0.001258525,0.0001212046,0.00006535846,0.0005750974,0.0002971143,0.004908696],"genre_scores_gemma":[0.9931874,0.003185404,0.00184745,0.00005528183,0.00001767481,0.00001637563,0.0002137184,0.00001342147,0.001463213],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001097047,"threshold_uncertainty_score":0.00487864,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1171832065257161,"score_gpt":0.3766912289220602,"score_spread":0.2595080223963441,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}