{"id":"W2021401577","doi":"10.1038/mt.2008.270","title":"Mesenchymal Stromal Cells Engineered to Express Erythropoietin Induce Anti-erythropoietin Antibodies and Anemia in Allorecipients","year":2008,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"Mesenchymal stem cell research","field":"Medicine","cited_by":49,"is_retracted":false,"has_abstract":false,"ca_institutions":"Jewish General Hospital; McGill University","funders":"","keywords":"Erythropoietin; Mesenchymal stem cell; Antibody; Stromal cell; Anemia; Cancer research; Cell biology; Immunology; Medicine; Biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004068369,0.0004124975,0.0006569641,0.0004314933,0.0001297319,0.00004163022,0.0002671642,0.0002354027,0.000269344],"category_scores_gemma":[0.0001027476,0.0003753955,0.0001205726,0.0005967834,0.0002604838,0.00009356003,0.0001747017,0.0005141193,0.00008684803],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000987556,"about_ca_system_score_gemma":0.000103402,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002284887,"about_ca_topic_score_gemma":0.000006415408,"domain_scores_codex":[0.996766,0.0002050263,0.0004668024,0.0007615024,0.0009390019,0.000861608],"domain_scores_gemma":[0.998604,0.00008234759,0.00006573302,0.0006116288,0.0001514948,0.0004847838],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004865465,0.0003312755,0.03943067,0.00007004356,0.00005101197,0.001698697,0.001450367,0.00007348559,0.9536046,0.00001420875,0.0008703451,0.001918747],"study_design_scores_gemma":[0.003998362,0.001176412,0.1722212,0.0001510698,0.00001195229,0.0002435896,0.0002293019,0.0001095935,0.8165112,0.0000128395,0.004882812,0.0004517314],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994324,0.001807003,0.0002731494,0.001344735,0.0002024975,0.001211928,0.00001079213,0.0000754752,0.0007504034],"genre_scores_gemma":[0.9937276,0.001301542,0.003553336,0.0005966381,0.00009546025,0.00005369635,0.00002473739,0.00008693185,0.0005600735],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1370934,"threshold_uncertainty_score":0.9998698,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02788029191589786,"score_gpt":0.2909041336711146,"score_spread":0.2630238417552168,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}