{"id":"W2021462093","doi":"10.1523/jneurosci.3503-05.2006","title":"Lipid Binding Regulates Synaptic Targeting of PICK1, AMPA Receptor Trafficking, and Synaptic Plasticity","year":2006,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":134,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Biological Sciences","funders":"Hong Kong University of Science and Technology","keywords":"PDZ domain; AMPA receptor; Postsynaptic density; Cell biology; Synaptic plasticity; Long-term depression; Biology; Chemistry; Receptor; Glutamate receptor; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007570077,0.0004529533,0.0003258975,0.0003607606,0.0003959363,0.0005577995,0.0002268817,0.0003448251,0.001125812],"category_scores_gemma":[0.0001165895,0.0002158306,0.0002829115,0.0002370738,0.0003028195,0.0003832341,0.0004788775,0.0005465895,0.0005821957],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008767888,"about_ca_system_score_gemma":0.0002604624,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001151142,"about_ca_topic_score_gemma":0.001336614,"domain_scores_codex":[0.9998299,0.00001453509,0.00001300461,0.00003327863,0.000058328,0.00005104673],"domain_scores_gemma":[0.9998971,0.000006945632,0.00004158082,0.000005439278,0.00001502166,0.00003386143],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001447657,0.00001531075,0.0003518779,0.00004474951,0.000008212923,0.0001330344,0.00001227263,0.00007770098,0.9973304,0.0001862333,0.00003932931,0.001656046],"study_design_scores_gemma":[0.0000277385,0.0001361984,0.04770624,0.00001499288,0.00005396112,0.001195164,0.00007437607,0.001511855,0.9442274,0.0003859288,0.004641209,0.00002500973],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9863936,0.009176968,0.001559234,0.0001371859,0.00003224599,0.00001458932,0.0002518152,0.0001225545,0.002311816],"genre_scores_gemma":[0.9932253,0.003522622,0.0008255792,0.00006145557,0.00001481442,0.00001751679,0.0002982124,0.00002494648,0.002009649],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001151142,"threshold_uncertainty_score":0.006361544,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03553144423055163,"score_gpt":0.3023972014423562,"score_spread":0.2668657572118046,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}