{"id":"W2021491888","doi":"10.1016/j.jaci.2008.12.548","title":"Tolerogenic Dendritic Cells Induce the Differentiation of CD4+CD25+Foxp3+ T Regulatory Cells from CD4+CD25−Foxp3− T Effectors cells and Reverse Asthma Phenotype Responses in an IL-10-dependent Fashion","year":2009,"lang":"en","type":"article","venue":"Journal of Allergy and Clinical Immunology","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"FOXP3; IL-2 receptor; Immunology; Adoptive cell transfer; Interleukin 10; Interleukin 4; Cytokine; Medicine; Biology; Cell biology; T cell; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003729856,0.000670425,0.0005465476,0.0005448922,0.0002245401,0.0005050867,0.0002806596,0.000452315,0.00230299],"category_scores_gemma":[0.0003057573,0.0002499612,0.0004714325,0.0002056745,0.0003592079,0.0002730411,0.0004445897,0.0025621,0.0008828297],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002384069,"about_ca_system_score_gemma":0.0004014883,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003412027,"about_ca_topic_score_gemma":0.0008554453,"domain_scores_codex":[0.9993621,0.0001054373,0.00004719031,0.00009202076,0.0001502865,0.0002430658],"domain_scores_gemma":[0.999649,0.00006646597,0.00007335961,0.0000487906,0.00005037665,0.0001118351],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003546919,0.0002152852,0.0004084817,0.000113949,0.00001428787,0.0001872088,0.00004459033,0.0001430429,0.9916688,0.0003107211,0.0002602974,0.006278688],"study_design_scores_gemma":[0.0003837771,0.001413499,0.005195667,0.00003806545,0.00006308978,0.000583422,0.00009711171,0.00142786,0.981015,0.0003194624,0.009448644,0.00001450866],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9846106,0.002731729,0.005809335,0.0003300784,0.0003283751,0.0002901818,0.0004040311,0.0004193333,0.005076269],"genre_scores_gemma":[0.987703,0.001541826,0.002807746,0.0002818643,0.0001622039,0.0001406298,0.0004523692,0.00008898235,0.006821295],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00230299,"threshold_uncertainty_score":0.007704318,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01716435477294561,"score_gpt":0.2920837378485717,"score_spread":0.2749193830756261,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}