{"id":"W2021492847","doi":"10.1016/s0168-9525(03)00135-5","title":"Telomere maintenance and DNA replication: how closely are these two connected?","year":2003,"lang":"en","type":"review","venue":"Trends in Genetics","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":94,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Sherbrooke","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"Semiconservative replication; Biology; Telomere; DNA replication; Telomerase; Pre-replication complex; Eukaryotic DNA replication; Genetics; Control of chromosome duplication; Minichromosome maintenance; Origin recognition complex; DNA; Cell biology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002194998,0.001434319,0.004945179,0.001681217,0.0009313298,0.004244299,0.002599819,0.005569693,0.004192305],"category_scores_gemma":[0.002750378,0.0005115265,0.000556202,0.00309321,0.002739248,0.006678639,0.001535971,0.00566266,0.002986549],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001576922,"about_ca_system_score_gemma":0.003010363,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001816779,"about_ca_topic_score_gemma":0.003326651,"domain_scores_codex":[0.9992256,0.000186726,0.00009410203,0.0001299347,0.0002867543,0.00007693557],"domain_scores_gemma":[0.998553,0.0007206806,0.0001835842,0.00004669575,0.0003147156,0.0001813115],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003824633,0.0001247298,0.000862525,0.009598841,0.0001949412,0.0006662703,0.0004544888,0.0004456087,0.00371603,0.01734096,0.05543834,0.9107748],"study_design_scores_gemma":[0.00007035562,0.0001235096,0.002170017,0.003735577,0.0001397972,0.00231687,0.0007868916,0.0001353152,0.0004373286,0.01784427,0.9721882,0.00005177235],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001258089,0.9961233,0.0002405021,0.002223723,0.0005750997,0.000002213782,0.000006125753,0.000008441777,0.0006947046],"genre_scores_gemma":[0.0009529794,0.9960027,0.000305631,0.001092454,0.001099724,0.000007575854,0.00001417455,0.000001618882,0.0005230139],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005569693,"threshold_uncertainty_score":0.01402462,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0989053256845764,"score_gpt":0.3763207605119152,"score_spread":0.2774154348273388,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}