{"id":"W2021559903","doi":"10.1021/bi048359d","title":"Novel Activity of RGS14 on Goα and Giα Nucleotide Binding and Hydrolysis Distinct from Its RGS Domain and GDI Activity","year":2005,"lang":"en","type":"article","venue":"Biochemistry","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences","keywords":"Nucleotide; Chemistry; Domain (mathematical analysis); ATP hydrolysis; Hydrolysis; Biochemistry; Enzyme; Mathematics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001462988,0.0004780459,0.0003313939,0.0001683456,0.0001013617,0.0002212933,0.0003308138,0.0002603485,0.0009628885],"category_scores_gemma":[0.000128393,0.0001727273,0.0005284584,0.0001115823,0.0002688668,0.0001442489,0.0002596484,0.0002872241,0.0004220393],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003209625,"about_ca_system_score_gemma":0.0001820032,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005013355,"about_ca_topic_score_gemma":0.0007351373,"domain_scores_codex":[0.9998418,0.00002545224,0.00001540953,0.00003681872,0.00004368959,0.00003680984],"domain_scores_gemma":[0.9999187,0.00001183148,0.00002043002,0.00001618821,0.000009983362,0.00002287399],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007556356,0.000008687403,0.0001530503,0.00002119496,0.000004438788,0.00003934081,0.00000447071,0.00002980279,0.9990215,0.00008737009,0.00001300233,0.0005415922],"study_design_scores_gemma":[0.00002077755,0.0001953657,0.00750656,0.000006398091,0.0000173373,0.0006124356,0.00001358258,0.000818945,0.9888304,0.00003443937,0.001939081,0.000004800108],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967007,0.0009179155,0.001167363,0.00004685236,0.00001170228,0.00001262899,0.000128737,0.00003681404,0.0009773251],"genre_scores_gemma":[0.9932555,0.000527732,0.00290908,0.00006845789,0.00001260675,0.00002242629,0.0009947731,0.00001895986,0.002190542],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009628885,"threshold_uncertainty_score":0.003221154,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01096943735149934,"score_gpt":0.236764858279571,"score_spread":0.2257954209280717,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}