{"id":"W2021608460","doi":"10.1161/01.res.0000168327.22888.4d","title":"Endotoxin-Induced Myocardial Dysfunction","year":2005,"lang":"en","type":"article","venue":"Circulation Research","topic":"Macrophage Migration Inhibitory Factor","field":"Immunology and Microbiology","cited_by":118,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; Société de Réanimation de Langue Française; Heart and Stroke Foundation of Canada","keywords":"Macrophage migration inhibitory factor; Autocrine signalling; Western blot; Apoptosis; Lipopolysaccharide; Paracrine signalling; Pharmacology; Tumor necrosis factor alpha; Cytokine; Internal medicine; Medicine; Immunology; Endocrinology; Biology; Receptor; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0008562076,0.000103323,0.0001267963,0.0002966619,0.0004157617,0.00004943989,0.0001387173,0.0002313658,0.005083547],"category_scores_gemma":[0.0002837855,0.0001035321,0.00007709902,0.0003183515,0.0001115462,0.0002169704,0.0000503977,0.0004874632,0.01028768],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001834619,"about_ca_system_score_gemma":0.0001033348,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007100555,"about_ca_topic_score_gemma":0.00003770788,"domain_scores_codex":[0.9983273,0.0005607957,0.0002503718,0.0003144737,0.0001558391,0.0003912376],"domain_scores_gemma":[0.9990643,0.0002046365,0.00004753954,0.0003213969,0.0003259198,0.0000362118],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004505508,0.00005529973,0.004100553,0.000005114415,0.00003578286,0.000001355086,0.0003201525,0.0002373281,0.9653058,0.0009033559,0.0131055,0.0158847],"study_design_scores_gemma":[0.002647671,0.000157292,0.1389912,0.00001702374,0.00001588079,0.00004717701,0.0003202534,0.000669546,0.610483,0.0002852055,0.2460283,0.0003374144],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9876539,0.0003037919,0.0005711408,0.0006975855,0.0007946112,0.0004315567,0.000008305673,0.0001275815,0.0094115],"genre_scores_gemma":[0.995266,0.000005024242,0.00002990743,0.00008467803,0.00042422,0.00007160485,0.00009561599,0.00001679402,0.004006145],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3548228,"threshold_uncertainty_score":0.9958259,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07917705839180574,"score_gpt":0.3469187143182463,"score_spread":0.2677416559264406,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}