{"id":"W2021773905","doi":"10.1182/blood-2009-01-200048","title":"The transcriptional program controlled by the stem cell leukemia gene Scl/Tal1 during early embryonic hematopoietic development","year":2009,"lang":"en","type":"article","venue":"Blood","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":120,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"BC Cancer Agency; Cancer Research UK","keywords":"Biology; Stem cell; Hematopoietic stem cell; Chromatin immunoprecipitation; Transgene; Embryonic stem cell; Haematopoiesis; Cell biology; Progenitor cell; Chromatin; Computational biology; Genetics; Gene; Gene expression; Promoter","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001740703,0.0001746379,0.0001459331,0.00001029123,0.0003924215,0.0001026795,0.0003260292,0.000100507,0.000004081781],"category_scores_gemma":[0.000003243945,0.0001094782,0.0001253837,0.00004702497,0.00005275235,0.000002047622,0.00003670137,0.0001054568,0.00001280381],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000278134,"about_ca_system_score_gemma":0.0001595852,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001952856,"about_ca_topic_score_gemma":0.000009350185,"domain_scores_codex":[0.9989721,0.00004246556,0.0002608425,0.0002449892,0.0001632748,0.0003162994],"domain_scores_gemma":[0.9994842,0.0000107449,0.00009564081,0.0003013513,0.00004584157,0.00006216846],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008650967,0.0002584513,0.0001571138,0.00001319445,0.0001169218,0.000002601145,0.0001560761,0.00003512097,0.9971861,0.00005974858,0.0001063208,0.001821876],"study_design_scores_gemma":[0.01404746,0.0005617584,0.01923071,0.00002265528,0.0001712027,0.0001261253,0.0003392319,0.0002634276,0.9513896,0.0001125072,0.01314467,0.00059071],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947618,0.003845186,0.0000763178,0.0001521862,0.00005674467,0.0005495001,0.00001029143,0.000020382,0.0005275892],"genre_scores_gemma":[0.9959913,0.0001755355,0.0004995799,0.00008624081,0.00007248981,0.0001145731,0.00004698185,0.00001826013,0.002995064],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04579652,"threshold_uncertainty_score":0.4464392,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003612695026348256,"score_gpt":0.1848055666300215,"score_spread":0.1811928716036732,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}