{"id":"W2021803277","doi":"10.1097/qad.0000000000000493","title":"Preexposure prophylaxis is efficacious for HIV-1 prevention among women using depot medroxyprogesterone acetate for contraception","year":2014,"lang":"en","type":"article","venue":"AIDS","topic":"HIV/AIDS Research and Interventions","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"National Institute of Allergy and Infectious Diseases; Eunice Kennedy Shriver National Institute of Child Health and Human Development; University of Washington","keywords":"Medroxyprogesterone acetate; Hormonal contraception; Medicine; Serodiscordant; Gynecology; Pre-exposure prophylaxis; Obstetrics; Family planning; Medroxyprogesterone; Population; Vaginal microbicide; Emtricitabine; Human immunodeficiency virus (HIV); Microbicides for sexually transmitted diseases; Viral load; Estrogen; Internal medicine; Family medicine; Syphilis; Antiretroviral therapy; Research methodology; Health services; Men who have sex with men","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001816246,0.0002426167,0.0006649614,0.0002221139,0.0001682969,0.0002904299,0.0002206177,0.0005513611,0.003112643],"category_scores_gemma":[0.004137855,0.0002376122,0.0007421231,0.0001334,0.0003846374,0.0003236904,0.0001826809,0.0005542561,0.0001260021],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001314514,"about_ca_system_score_gemma":0.0002424244,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002616923,"about_ca_topic_score_gemma":0.0005041579,"domain_scores_codex":[0.999007,0.0005775645,0.00008166589,0.00007910478,0.0001491352,0.00010557],"domain_scores_gemma":[0.9983187,0.0009865984,0.0004182394,0.00006600433,0.00005669692,0.0001538952],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.5296823,0.02115309,0.07512373,0.00331565,0.003870207,0.0001535457,0.0003894886,0.0007035392,0.02015343,0.0003120616,0.001019212,0.3441238],"study_design_scores_gemma":[0.1059428,0.4561888,0.4191874,0.0006816221,0.004614196,0.0004591808,0.0001830267,0.00105345,0.007785257,0.0003073607,0.003568058,0.00002873828],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921985,0.006364665,0.0001120765,0.0001581867,0.00004558942,0.0001486109,0.00008320717,0.000008953874,0.0008802395],"genre_scores_gemma":[0.9977633,0.001506525,0.0001845181,0.0001197938,0.0001022752,0.00006986825,0.00007114131,0.000001309356,0.0001813005],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003112643,"threshold_uncertainty_score":0.01041281,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02688921386669214,"score_gpt":0.3297077135315641,"score_spread":0.302818499664872,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}