{"id":"W2021803277","doi":"10.1097/qad.0000000000000493","title":"Preexposure prophylaxis is efficacious for HIV-1 prevention among women using depot medroxyprogesterone acetate for contraception","year":2014,"lang":"en","type":"article","venue":"AIDS","topic":"HIV/AIDS Research and Interventions","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"National Institute of Allergy and Infectious Diseases; Eunice Kennedy Shriver National Institute of Child Health and Human Development; University of Washington","keywords":"Medroxyprogesterone acetate; Hormonal contraception; Medicine; Serodiscordant; Gynecology; Pre-exposure prophylaxis; Obstetrics; Family planning; Medroxyprogesterone; Population; Vaginal microbicide; Emtricitabine; Human immunodeficiency virus (HIV); Microbicides for sexually transmitted diseases; Viral load; Estrogen; Internal medicine; Family medicine; Syphilis; Antiretroviral therapy; Research methodology; Health services; Men who have sex with men","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007023396,0.0001592496,0.000327871,0.0001538478,0.0001624561,0.00004970467,0.0001005634,0.0001340127,0.0001405098],"category_scores_gemma":[0.0004658838,0.0001388057,0.0002709259,0.0001399075,0.00008822299,0.0002044591,0.00002977438,0.0001398237,0.00002919923],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001332967,"about_ca_system_score_gemma":0.00005936789,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001141655,"about_ca_topic_score_gemma":0.00001583291,"domain_scores_codex":[0.9984539,0.00009434973,0.0003696325,0.0003297359,0.0002546845,0.0004977057],"domain_scores_gemma":[0.9989864,0.00009761182,0.0001222879,0.0002951938,0.0002712613,0.0002272327],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.002144015,0.001244953,0.05425132,0.00239182,0.0007734332,0.000003926821,0.002540584,0.00003533431,0.1236551,0.0004313845,0.01259318,0.799935],"study_design_scores_gemma":[0.06417417,0.3742872,0.05512792,0.003619642,0.001507144,0.0001496396,0.002668878,0.2217968,0.1513578,0.006613669,0.1167883,0.001908856],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7743009,0.00007091266,0.2229197,0.0001989405,0.00004549221,0.002183405,0.00005216596,0.00005579372,0.0001727197],"genre_scores_gemma":[0.9707997,0.000007073278,0.01053983,0.00004509856,0.0002713022,0.001023491,0.0001209256,0.00004371091,0.01714886],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7980261,"threshold_uncertainty_score":0.5660331,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02688921386669214,"score_gpt":0.3297077135315641,"score_spread":0.302818499664872,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}