{"id":"W2021811627","doi":"10.1016/j.peptides.2003.07.011","title":"Identification of a binding site for the anti-inflammatory tripeptide feG","year":2003,"lang":"en","type":"article","venue":"Peptides","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Tripeptide; Chemistry; Binding site; Peptide; In silico; Enzyme; Protein kinase A; Biochemistry; Molecular model; Active site; Mechanism of action; Biophysics; Stereochemistry; In vitro; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004654576,0.00007567216,0.00007924913,0.00003247181,0.0001131792,0.00001859407,0.00008129597,0.00005428877,0.00001004549],"category_scores_gemma":[0.0002511856,0.0000596661,0.00009678549,0.00006399902,0.0000550416,0.00000388661,0.00001452924,0.00002784771,0.000007923724],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006195494,"about_ca_system_score_gemma":0.00003692894,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002308041,"about_ca_topic_score_gemma":0.000005046045,"domain_scores_codex":[0.999391,0.00003876221,0.000221891,0.0001522436,0.00007953576,0.000116567],"domain_scores_gemma":[0.9994951,0.00003266694,0.0001435493,0.0002214204,0.00008263694,0.00002457136],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001553745,0.00001200599,0.001165003,0.00002909439,0.0000229482,1.624225e-7,0.00003270063,0.0002526547,0.9964864,0.0007547315,0.0004355835,0.0007931232],"study_design_scores_gemma":[0.0002850626,0.00002510419,0.001484715,0.00001509638,0.00001939784,0.000002507086,0.00006821454,0.0002718978,0.9672774,0.0001166046,0.03035382,0.00008018426],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9777439,0.001153224,0.02040092,0.00005953519,0.00009433033,0.0003548016,0.00002478393,0.000009277566,0.0001592427],"genre_scores_gemma":[0.9984711,0.00007649921,0.0005882526,0.00003541232,0.00007834047,0.00005362954,0.00003830781,0.0000120842,0.0006463215],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02991823,"threshold_uncertainty_score":0.2433113,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01235206807143758,"score_gpt":0.2522932150996776,"score_spread":0.23994114702824,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}