{"id":"W2021818925","doi":"10.1086/526788","title":"Potent Antimalarial and Transmission‐Blocking Activities of Centanamycin, a Novel DNA‐Binding Agent","year":2008,"lang":"en","type":"article","venue":"The Journal of Infectious Diseases","topic":"Malaria Research and Control","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Biology; Malaria; Parasite hosting; Plasmodium (life cycle); Virology; Transmission (telecommunications); In vivo; Plasmodium falciparum; DNA; Gametocyte; Host (biology); Anopheles; Immunology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002733289,0.0001119638,0.0003355592,0.0001795385,0.0001986671,0.0000132619,0.00007938832,0.0000355844,0.0000855614],"category_scores_gemma":[0.000183387,0.00006628715,0.0001776211,0.0001222334,0.0001521105,0.0001137154,0.00002657001,0.0002261364,6.021529e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005308925,"about_ca_system_score_gemma":0.0002581522,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004078481,"about_ca_topic_score_gemma":0.000002301463,"domain_scores_codex":[0.9988479,0.0000928894,0.0003214629,0.00007018583,0.0004673536,0.0002002177],"domain_scores_gemma":[0.9990577,0.0001953118,0.0002360775,0.0001109318,0.000148049,0.0002519052],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.01430861,0.003759335,0.2562285,0.0006555245,0.002355292,0.0008751948,0.003829301,0.0003688917,0.6867797,0.0004586996,0.001700325,0.02868057],"study_design_scores_gemma":[0.02720228,0.005308377,0.9014201,0.001389679,0.002552828,0.01383745,0.002181492,0.001266714,0.04303171,0.0002936752,0.001117612,0.0003981197],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952688,0.00136192,0.001863739,0.0008442989,0.0001047959,0.000206382,0.00001296252,0.00001105019,0.0003260961],"genre_scores_gemma":[0.9979881,0.001543758,0.00004896405,0.00008363191,0.0002535997,0.000001650817,0.000001007295,0.00001195611,0.00006733873],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6451916,"threshold_uncertainty_score":0.2703111,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01588578205373118,"score_gpt":0.2584118305889447,"score_spread":0.2425260485352135,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}