{"id":"W2021818925","doi":"10.1086/526788","title":"Potent Antimalarial and Transmission‐Blocking Activities of Centanamycin, a Novel DNA‐Binding Agent","year":2008,"lang":"en","type":"article","venue":"The Journal of Infectious Diseases","topic":"Malaria Research and Control","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Biology; Malaria; Parasite hosting; Plasmodium (life cycle); Virology; Transmission (telecommunications); In vivo; Plasmodium falciparum; DNA; Gametocyte; Host (biology); Anopheles; Immunology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001200294,0.0002769764,0.0001764977,0.000279497,0.0001265875,0.000201482,0.0001505759,0.0001815801,0.0008372646],"category_scores_gemma":[0.0001196679,0.0001043392,0.0001103893,0.000103391,0.0002100529,0.0001584157,0.0001465147,0.0003743061,0.0001690553],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001184307,"about_ca_system_score_gemma":0.0001381236,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003877943,"about_ca_topic_score_gemma":0.0007310034,"domain_scores_codex":[0.9999522,0.00001131882,0.000003361783,0.000007638693,0.00001454537,0.00001096206],"domain_scores_gemma":[0.9999316,0.00001493238,0.00001676765,0.000007881836,0.000009345426,0.00001949665],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009629389,0.00001880009,0.00008944201,0.00006192944,0.000003632118,0.00003646065,0.00001036519,0.00006226332,0.9950735,0.0001279248,0.00004638659,0.004373019],"study_design_scores_gemma":[0.00003165609,0.001317386,0.003715177,0.00001121214,0.0000180819,0.0006135025,0.000009120356,0.0003028037,0.9871814,0.00004706289,0.006747101,0.000005542337],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9726282,0.01850543,0.003574194,0.0001705121,0.00004901962,0.00006602164,0.0003500457,0.0001047253,0.004551828],"genre_scores_gemma":[0.9928872,0.003170242,0.002184136,0.00004337987,0.00002021282,0.0000241616,0.0002302696,0.000007175513,0.001433094],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008372646,"threshold_uncertainty_score":0.002800941,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01588578205373118,"score_gpt":0.2584118305889447,"score_spread":0.2425260485352135,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}