{"id":"W2021846751","doi":"10.1111/j.1471-4159.2005.03002.x","title":"Extracellular signal‐regulated kinase 1/2 mediates survival, but not axon regeneration, of adult injured central nervous system neurons <i>in vivo</i>","year":2005,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Nerve injury and regeneration","field":"Neuroscience","cited_by":74,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"U.S. Public Health Service; National Institutes of Health; Glaucoma Foundation; Glaucoma Research Foundation","keywords":"Biology; Axon; Cell biology; Neuroscience; Neurotrophin; Signal transduction; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001349566,0.0005518145,0.000230893,0.0001784579,0.0001656654,0.0003425752,0.0001985252,0.0002262462,0.0008567068],"category_scores_gemma":[0.00007688268,0.0001240663,0.0002504459,0.00008111857,0.0002246217,0.0002045422,0.0001750035,0.0005319879,0.0004079895],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003264688,"about_ca_system_score_gemma":0.000277779,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001058879,"about_ca_topic_score_gemma":0.001684834,"domain_scores_codex":[0.9999007,0.000009737314,0.000007447397,0.00002279797,0.00002799949,0.00003130409],"domain_scores_gemma":[0.9999514,0.000006203697,0.00001369798,0.000006514862,0.000007346656,0.00001479919],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004860245,0.00001577758,0.00009436956,0.00004870713,0.000003207954,0.00002734156,0.000008715951,0.00003220804,0.9984758,0.00006343774,0.00004531258,0.001136491],"study_design_scores_gemma":[0.00001613044,0.000234443,0.01149601,0.00001195374,0.00001895097,0.0003684859,0.00002188723,0.0008365168,0.9845615,0.00004859604,0.002381071,0.000004514031],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.988476,0.003740766,0.003465449,0.0001344153,0.00003992394,0.00002403275,0.0003846061,0.00015798,0.003576789],"genre_scores_gemma":[0.9862839,0.00315225,0.003706608,0.00008511708,0.00002775303,0.00007113236,0.0008243802,0.00003338673,0.005815473],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001058879,"threshold_uncertainty_score":0.002865911,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01461455048196728,"score_gpt":0.2293272410863182,"score_spread":0.2147126906043509,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}