{"id":"W2021884419","doi":"10.1107/s1744309105010997","title":"Crystallization and preliminary X-ray analysis of (1<i>R</i>,6<i>R</i>)-2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) synthase (MenD) from<i>Escherichia coli</i>","year":2005,"lang":"en","type":"article","venue":"Acta Crystallographica Section F Structural Biology and Crystallization Communications","topic":"Biochemical Acid Research Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"National Center for Research Resources","keywords":"Carboxylate; Crystallization; Enzyme; Cofactor; Crystallography; Chemistry; Stereochemistry; Ethylene glycol; Adduct; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002717173,0.0003803073,0.0005071566,0.000437187,0.000614286,0.00005681696,0.0005192407,0.0004928336,0.00005469594],"category_scores_gemma":[0.00022252,0.0003603188,0.0001891673,0.001243464,0.001238871,0.00005885086,0.0007167387,0.0003180944,1.32362e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002873902,"about_ca_system_score_gemma":0.00004760851,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000172532,"about_ca_topic_score_gemma":0.0006795129,"domain_scores_codex":[0.9976155,0.0004156288,0.0006847695,0.0007241853,0.0001825607,0.0003773727],"domain_scores_gemma":[0.997793,0.0002042838,0.0004090766,0.001031834,0.0003633407,0.000198502],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002470532,0.00008988102,0.01625761,0.00002752536,0.001388344,2.503325e-7,0.0002238463,0.0003318997,0.9802893,0.0004080242,0.0001035856,0.000632646],"study_design_scores_gemma":[0.006588326,0.004053612,0.6168212,0.0001985381,0.006302575,0.00003575672,0.002081975,0.05276724,0.07892548,0.005119587,0.2233684,0.003737384],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9882751,0.004398298,0.004784336,0.001268987,0.00006943951,0.0004564399,0.0003886567,0.00006624043,0.0002925647],"genre_scores_gemma":[0.9811773,0.01100445,0.004139211,0.0002889372,0.0001137983,0.00008200503,0.00312413,0.00003062532,0.00003955302],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9013638,"threshold_uncertainty_score":0.9998849,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01034984986910842,"score_gpt":0.2669273138555366,"score_spread":0.2565774639864282,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}