{"id":"W2021901688","doi":"10.1038/cr.2009.55","title":"The adenoviral E1A protein displaces corepressors and relieves gene repression by unliganded thyroid hormone receptors in vivo","year":2009,"lang":"en","type":"article","venue":"Cell Research","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"Mount Sinai Hospital; Western University","funders":"National Institutes of Health","keywords":"Corepressor; Biology; Psychological repression; Coactivator; Thyroid hormone receptor; Nuclear receptor; Repressor; Cell biology; Receptor; Regulation of gene expression; Molecular biology; Gene; Gene expression; Transcription factor; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002317706,0.0001998471,0.0001717307,0.0001194437,0.000438321,0.0001407871,0.0006132965,0.000232378,0.00002706615],"category_scores_gemma":[0.0002902149,0.0001441478,0.00005157165,0.0003060616,0.0004496015,0.00001156172,0.0003005924,0.0005674229,0.00001115232],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004597284,"about_ca_system_score_gemma":0.0001371869,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007258612,"about_ca_topic_score_gemma":0.0001131857,"domain_scores_codex":[0.9967991,0.0006883912,0.0002864377,0.0007121192,0.0007086951,0.0008052536],"domain_scores_gemma":[0.9986799,0.0001017313,0.00005980965,0.0008002149,0.0001580645,0.000200265],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004124212,0.0001233719,0.0002010055,0.00000862625,0.0000101671,0.000008105541,0.0001230088,0.00001269395,0.9681659,0.000006506237,0.01890079,0.008315647],"study_design_scores_gemma":[0.00102793,0.003711625,0.0003340636,0.00001944722,0.000001810146,0.000002618398,0.0001765365,0.00006692917,0.9770907,0.000271239,0.01711887,0.0001782326],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9721925,0.02385652,0.000007856387,0.001020016,0.0000262149,0.0008278939,0.00001266523,0.0000134802,0.002042802],"genre_scores_gemma":[0.9768811,0.01009095,0.00005373078,0.00004771758,0.0001070912,0.0001076442,0.00003808508,0.00003251737,0.01264114],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01376557,"threshold_uncertainty_score":0.5878178,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01791384115478156,"score_gpt":0.3194879477392357,"score_spread":0.3015741065844541,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}