{"id":"W2022021686","doi":"10.1016/j.cellsig.2013.07.002","title":"Aldosterone signaling through transient receptor potential melastatin 7 cation channel (TRPM7) and its α-kinase domain","year":2013,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Magnesium in Health and Disease","field":"Nursing","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Ottawa Hospital; University of Ottawa","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institutes of Health; Canada Foundation for Innovation; British Heart Foundation; Heart and Stroke Foundation of Canada; Office of Dietary Supplements","keywords":"TRPM7; Aldosterone; Kinase; Protein kinase domain; Cell biology; Chemistry; Cyclin-dependent kinase 9; Signal transduction; ASK1; Biology; Molecular biology; Mitogen-activated protein kinase kinase; Protein kinase A; Endocrinology; Biochemistry; Receptor; Transient receptor potential channel; Mutant","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003572783,0.0003160295,0.0002958126,0.0001125569,0.000440105,0.0001558994,0.0001593761,0.0001591999,0.0009765221],"category_scores_gemma":[0.00006359906,0.0003281012,0.0000956529,0.0002009283,0.00005671612,0.0004664163,0.00003261528,0.0002470675,0.0002387946],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007030304,"about_ca_system_score_gemma":0.00004262164,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002368002,"about_ca_topic_score_gemma":0.000005712703,"domain_scores_codex":[0.9975355,0.0002427097,0.0005754561,0.0005755856,0.0003993996,0.0006713924],"domain_scores_gemma":[0.9988537,0.0001333319,0.0001894773,0.0002045059,0.0001807856,0.0004381698],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002903236,0.0001548852,0.00001963325,0.0007685547,0.00001043841,0.00002171229,0.005905306,0.001719808,0.9881977,0.0001449497,0.0002888698,0.002477765],"study_design_scores_gemma":[0.004892845,0.0007497307,0.0002590614,0.000389424,0.0003017852,0.00002118647,0.005424342,0.06836205,0.9085912,0.007580358,0.001871191,0.001556789],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.949844,0.004812457,0.04118078,0.001835412,0.0009965919,0.00101195,0.00002481452,0.0001341639,0.0001598482],"genre_scores_gemma":[0.9938617,0.00002034345,0.004472274,0.0006811519,0.0005600288,0.0001152912,0.0001528469,0.00006358598,0.00007278668],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07960652,"threshold_uncertainty_score":0.9999367,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01566003259041369,"score_gpt":0.2331260863765695,"score_spread":0.2174660537861557,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}