{"id":"W2022046169","doi":"10.1089/cbr.2006.21.613","title":"Human Dendritic Cells Engineered to Express Alpha Tumor Necrosis Factor Maintain Cellular Maturation and T-Cell Stimulation Capacity","year":2006,"lang":"en","type":"article","venue":"Cancer Biotherapy and Radiopharmaceuticals","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Saskatchewan Cancer Agency","funders":"","keywords":"Tumor necrosis factor alpha; Ex vivo; Immunology; Dendritic cell; Immune system; Cytokine; Peripheral blood mononuclear cell; Biology; Granulocyte macrophage colony-stimulating factor; In vivo; Cancer research; Medicine; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001701568,0.0002216118,0.0002811792,0.00009364191,0.00007967088,0.0003088727,0.0001272942,0.0001841522,0.0005472046],"category_scores_gemma":[0.0002384694,0.00009517238,0.0001777453,0.0001596738,0.0001355939,0.000142418,0.0001160389,0.0004119522,0.0004092133],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001833972,"about_ca_system_score_gemma":0.0001528297,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001951837,"about_ca_topic_score_gemma":0.0001878906,"domain_scores_codex":[0.9998554,0.00002237409,0.00001926774,0.00003448217,0.00003763507,0.00003069943],"domain_scores_gemma":[0.999835,0.00003306835,0.00003909309,0.00003534951,0.00003770774,0.00001982867],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00014786,0.00003446861,0.0002623984,0.00003116615,0.000003663596,0.00002921627,0.00001442427,0.0001171413,0.9973502,0.00007434499,0.00003569003,0.001899234],"study_design_scores_gemma":[0.00002523759,0.000321791,0.001070876,0.000005136608,0.00001958616,0.0001921553,0.000007985211,0.0005344838,0.9927059,0.00003920384,0.005074071,0.000003508251],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9809925,0.004326849,0.01160834,0.00008961225,0.00009622989,0.0001285129,0.0008761844,0.00009301268,0.001788724],"genre_scores_gemma":[0.9873241,0.001658187,0.007016308,0.00007436609,0.00002560214,0.00006915723,0.001443433,0.0000243822,0.002364267],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005472046,"threshold_uncertainty_score":0.001830578,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01877552616447341,"score_gpt":0.2825533646841403,"score_spread":0.2637778385196669,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}