{"id":"W2022052232","doi":"10.1002/mc.20406","title":"Attenuation of DNA damage‐induced p53 expression by arsenic: A possible mechanism for arsenic co‐carcinogenesis","year":2007,"lang":"en","type":"article","venue":"Molecular Carcinogenesis","topic":"Arsenic contamination and mitigation","field":"Environmental Science","cited_by":73,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Nucleotide excision repair; DNA repair; Xeroderma pigmentosum; Biology; DNA damage; Carcinogenesis; Molecular biology; Transcription factor II H; DNA; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006749292,0.0002840955,0.0003002897,0.0001453769,0.0002049274,0.00001967576,0.000272857,0.0002102316,0.0002437835],"category_scores_gemma":[0.0001121926,0.0002983327,0.0002575477,0.0003872403,0.00008829375,0.0001868092,0.0001143434,0.00007557227,0.00004564666],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002263253,"about_ca_system_score_gemma":0.00003895267,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002354446,"about_ca_topic_score_gemma":0.0001238537,"domain_scores_codex":[0.9976211,0.00009549135,0.0005648778,0.0005913624,0.0006554764,0.000471647],"domain_scores_gemma":[0.9987745,0.000100471,0.0003210751,0.000515014,0.00009532545,0.0001935764],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004783314,0.0001086386,0.004854866,0.00002175211,0.00002081848,0.00000793508,0.0003255212,0.00002693043,0.9868866,0.0008734319,0.0003362677,0.006489474],"study_design_scores_gemma":[0.0009343886,0.0001356497,0.0242559,0.00002067257,0.00008860286,0.000006508563,0.0003706206,0.0009423014,0.9720765,0.000395536,0.0004574959,0.0003158305],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8849173,0.00006301307,0.1119502,0.0001519877,0.0001037313,0.0007656112,0.00005044535,0.00005611711,0.001941598],"genre_scores_gemma":[0.9942356,0.00001126679,0.004684402,0.0003327203,0.00002565215,0.00008503938,0.0001594528,0.00005664517,0.0004092009],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1093184,"threshold_uncertainty_score":0.9999469,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01388655027620968,"score_gpt":0.2521649427287611,"score_spread":0.2382783924525514,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}