{"id":"W2022077813","doi":"10.1016/j.bbi.2011.02.017","title":"The critical role of the MyD88-dependent pathway in non-CNS MPTP-mediated toxicity","year":2011,"lang":"en","type":"article","venue":"Brain Behavior and Immunity","topic":"Gastrointestinal motility and disorders","field":"Medicine","cited_by":47,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"National Institutes of Health; National Institute of Mental Health; Banting Research Foundation; Canadian Institutes of Health Research; Université Laval","keywords":"MPTP; Myenteric plexus; Enteric nervous system; Dopaminergic; Microglia; Inflammation; Central nervous system; Biology; Neurotoxin; Dopamine; Neuroscience; Endocrinology; Immunology; Immunohistochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005157274,0.0001132241,0.0001796535,0.00003337431,0.0001811516,0.00001030848,0.0001815974,0.00007156211,0.00006962022],"category_scores_gemma":[0.001340295,0.00006793441,0.00007593147,0.0001303798,0.0004740267,0.00005224193,0.0001372037,0.000447013,0.000004233592],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000206216,"about_ca_system_score_gemma":0.00006595711,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001580668,"about_ca_topic_score_gemma":0.0006541496,"domain_scores_codex":[0.9990263,0.0001763993,0.0002593918,0.0001278066,0.0001767846,0.0002333251],"domain_scores_gemma":[0.9990358,0.0003433579,0.00004519811,0.0004098707,0.00007693744,0.00008884221],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002757878,0.001493082,0.9099226,0.00003695632,0.000007173839,0.00001215641,0.002493867,8.514148e-8,0.07821354,0.0003414422,0.00004597414,0.007157351],"study_design_scores_gemma":[0.000698446,0.0002894651,0.985648,0.0000630756,0.00002820846,0.00004181521,0.003252763,0.00001806326,0.00947913,0.0003599469,0.00006273466,0.00005830692],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969485,0.000138944,0.00001087837,0.0006114299,0.00006377786,0.0003451856,0.00001830503,0.00001367671,0.001849256],"genre_scores_gemma":[0.9995856,0.00001097101,0.0000648368,0.0001884699,0.000008164327,0.00002560679,0.000004357624,0.000008320961,0.0001036887],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07572546,"threshold_uncertainty_score":0.2770285,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02304682814844093,"score_gpt":0.2630757851614683,"score_spread":0.2400289570130274,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}