{"id":"W2022135107","doi":"10.1016/j.immuni.2007.03.009","title":"Nod1-Mediated Innate Immune Recognition of Peptidoglycan Contributes to the Onset of Adaptive Immunity","year":2007,"lang":"en","type":"article","venue":"Immunity","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":332,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canada Research Chairs; University of Toronto; University of New Brunswick","funders":"Takeda Oncology","keywords":"Biology; Peptidoglycan; Innate immune system; NOD1; Acquired immune system; Immunity; Immunology; Immune system; Immune recognition; Pattern recognition receptor; NOD2; Virology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004987498,0.0004412487,0.0003870093,0.0003050018,0.0002380074,0.0008865474,0.0002614123,0.0004310088,0.001662131],"category_scores_gemma":[0.0003428658,0.0002380555,0.0002838406,0.0001422276,0.0003740553,0.0006854201,0.0007362879,0.001913643,0.0007566275],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004885116,"about_ca_system_score_gemma":0.000445738,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002902283,"about_ca_topic_score_gemma":0.0003742349,"domain_scores_codex":[0.9997528,0.00004296308,0.00001706094,0.00004438872,0.00005831055,0.00008448536],"domain_scores_gemma":[0.9996357,0.00003768559,0.00007457636,0.00003259187,0.00007410221,0.0001452432],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004844042,0.0000544195,0.00135327,0.0001633386,0.000006769294,0.0003039737,0.00003640364,0.0002029408,0.984559,0.000942357,0.0004195819,0.01147353],"study_design_scores_gemma":[0.00009645303,0.0007633517,0.06777634,0.000142609,0.00004984847,0.002508703,0.000288488,0.003938849,0.8975456,0.002258023,0.02458598,0.00004577651],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9463876,0.02638122,0.01456196,0.001404478,0.000367969,0.0000822915,0.0005668691,0.0003875726,0.009860023],"genre_scores_gemma":[0.9853138,0.00469257,0.00342905,0.000167376,0.0001318553,0.0000260695,0.0004362712,0.00003480721,0.005768193],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001662131,"threshold_uncertainty_score":0.005560398,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0177778603169823,"score_gpt":0.2480863898991355,"score_spread":0.2303085295821532,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}