{"id":"W2022168902","doi":"10.1038/tpj.2010.65","title":"Systematic analysis of dopamine receptor genes (DRD1–DRD5) in antipsychotic-induced weight gain","year":2010,"lang":"en","type":"article","venue":"The Pharmacogenomics Journal","topic":"Schizophrenia research and treatment","field":"Medicine","cited_by":67,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"National Institute of Mental Health; Canadian Institutes of Health Research","keywords":"Weight gain; Antipsychotic; Single-nucleotide polymorphism; Dopamine receptor D2; Schizoaffective disorder; Internal medicine; Medicine; Schizophrenia (object-oriented programming); Dopamine; Oncology; Endocrinology; Gene; Psychosis; Genetics; Biology; Psychiatry; Body weight; Genotype","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001601954,0.0001893714,0.0007012656,0.000746115,0.0001114926,0.00003923151,0.0003263357,0.00005839893,0.0006404789],"category_scores_gemma":[0.0001216557,0.0001113433,0.0003640946,0.0008773197,0.00007114646,0.00006297723,0.00004428431,0.0007334583,0.00005029542],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001251902,"about_ca_system_score_gemma":0.0002139154,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004010669,"about_ca_topic_score_gemma":0.000135737,"domain_scores_codex":[0.9980441,0.0002396286,0.0007318957,0.0001823031,0.0004337002,0.0003683656],"domain_scores_gemma":[0.9985082,0.0002835317,0.0003271466,0.0003992123,0.0001748894,0.0003070834],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003644148,0.0006253126,0.01722849,0.0004837059,0.005679992,0.0001718304,0.0003923557,0.0001063286,0.9662237,0.0001194058,0.000122074,0.005202619],"study_design_scores_gemma":[0.04371046,0.001372616,0.09210391,0.002419913,0.03048919,0.005077702,0.001029292,0.0713648,0.7496896,0.0007933253,0.0008195554,0.001129657],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959761,0.001384955,0.0001229573,0.001373134,0.0004871902,0.0005386554,0.00001630524,0.00001082887,0.0000899015],"genre_scores_gemma":[0.9969571,0.001467774,0.0009471575,0.00007675454,0.0003497028,0.00001883491,0.00001062147,0.00002578131,0.0001462935],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2165342,"threshold_uncertainty_score":0.7012795,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02828119449426986,"score_gpt":0.3346353232598315,"score_spread":0.3063541287655617,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}