{"id":"W2022225544","doi":"10.1016/j.str.2007.10.001","title":"Protease Yoga: Extreme Flexibility of a Matrix Metalloproteinase","year":2007,"lang":"en","type":"letter","venue":"Structure","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Proteases; Protease; Matrix metalloproteinase; Extracellular matrix; Chemistry; Computational biology; Biology; Cell biology; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005692784,0.0005931428,0.0007123876,0.0001426735,0.000560939,0.001061728,0.0006367135,0.004010912,0.001336672],"category_scores_gemma":[0.001344435,0.0002793126,0.0002474152,0.0001283153,0.001662472,0.001203758,0.0004789736,0.005391472,0.0009035316],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006952304,"about_ca_system_score_gemma":0.0002795748,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001276582,"about_ca_topic_score_gemma":0.0001929402,"domain_scores_codex":[0.9998152,0.00004514305,0.00001897984,0.00003494048,0.00005240552,0.00003334508],"domain_scores_gemma":[0.9996164,0.0002036003,0.00004589702,0.00003329222,0.00002650903,0.00007431705],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00460562,0.0002210936,0.002640592,0.0008232552,0.0001003844,0.04289877,0.0004694389,0.001593488,0.1146402,0.07632111,0.6280554,0.1276307],"study_design_scores_gemma":[0.001725691,0.001248975,0.004609286,0.0001661436,0.0001442069,0.05668062,0.0005399542,0.009822576,0.1080969,0.1224683,0.6943298,0.0001674806],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"other","genre_scores_codex":[0.0803111,0.0449875,0.01030943,0.7941249,0.05885234,0.00006986932,0.0001856532,0.0006321848,0.01052709],"genre_scores_gemma":[0.5069258,0.03730689,0.01293009,0.2843954,0.1208837,0.0002564782,0.0003295156,0.0001798739,0.0367922],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.004010912,"threshold_uncertainty_score":0.005044281,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01881617002162357,"score_gpt":0.2674940581285062,"score_spread":0.2486778881068827,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}