{"id":"W2022248355","doi":"10.1074/jbc.m503578200","title":"Sp1 Is a Co-activator with Ets-1, and Net Is an Important Repressor of the Transcription of CTP:Phosphocholine Cytidylyltransferase α","year":2005,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Institutes of Health Research; University of Alberta","funders":"","keywords":"Repressor; Transcription (linguistics); Molecular biology; Phosphocholine; Promoter; Transcription factor; Messenger RNA; Biology; Activator (genetics); Luciferase; Response element; Chemistry; Gene expression; Gene; Biochemistry; Phosphatidylcholine; Transfection; Phospholipid","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002094643,0.0007143697,0.0004492667,0.0003608235,0.0003937606,0.000327639,0.000336259,0.0003656461,0.002352027],"category_scores_gemma":[0.0002039193,0.0002930572,0.0005572474,0.0002913117,0.0003213201,0.0002443118,0.0004800965,0.0008842217,0.001361395],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004042375,"about_ca_system_score_gemma":0.0002486034,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008777943,"about_ca_topic_score_gemma":0.001072864,"domain_scores_codex":[0.999692,0.00003342039,0.00001877061,0.0001108632,0.00009626033,0.00004864568],"domain_scores_gemma":[0.9998332,0.00002888339,0.00004013747,0.00001332738,0.00003911006,0.00004529583],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002142539,0.00004693285,0.002332113,0.0001600457,0.00002314799,0.0002066876,0.00003505206,0.0001556159,0.9893365,0.0002676361,0.0004203083,0.006801717],"study_design_scores_gemma":[0.0000672759,0.0003828478,0.04015373,0.00004575147,0.0000735675,0.001914653,0.0001672993,0.005169362,0.9299114,0.0005102435,0.02157812,0.00002567473],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9440823,0.01568773,0.02932249,0.0005795308,0.0002924687,0.00009641228,0.002805335,0.0004940767,0.006639658],"genre_scores_gemma":[0.9698606,0.003736601,0.00742904,0.0002153671,0.00009956418,0.00009307932,0.006520799,0.00008433045,0.01196078],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002352027,"threshold_uncertainty_score":0.00786835,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02099923718921905,"score_gpt":0.2567806287595308,"score_spread":0.2357813915703118,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}