{"id":"W2022267121","doi":"10.1115/1.4000194","title":"Hydrostatic Pressure Stimulation of Human Mesenchymal Stem Cells Seeded on Collagen-Based Artificial Extracellular Matrices","year":2009,"lang":"en","type":"article","venue":"Journal of Biomechanical Engineering","topic":"Bone Tissue Engineering Materials","field":"Engineering","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Bone and Joint Health Institute; University of Calgary","funders":"Canadian Institutes of Health Research; Institute of Gender and Health; Deutscher Akademischer Austauschdienst; Calgary Foundation","keywords":"Mesenchymal stem cell; Extracellular matrix; Cell biology; Alkaline phosphatase; Chemistry; Stimulation; Extracellular; Tissue engineering; Hydrostatic pressure; Cell growth; Cellular differentiation; Stem cell; Biophysics; Biochemistry; Biomedical engineering; Endocrinology; Biology; Enzyme; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005033866,0.000295423,0.0006004752,0.0004960112,0.00003194897,0.00005335132,0.0002528521,0.000192805,0.00005455734],"category_scores_gemma":[0.00002958528,0.0002942288,0.0001707931,0.000408651,0.00001160288,0.0001555275,0.00001199437,0.000218108,0.000007889627],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008547489,"about_ca_system_score_gemma":0.00002166099,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001416291,"about_ca_topic_score_gemma":1.419763e-7,"domain_scores_codex":[0.9979391,0.00002813539,0.001058392,0.0001517034,0.0004981877,0.000324557],"domain_scores_gemma":[0.9991188,0.0001313623,0.0002573992,0.0002313227,0.00009276262,0.0001683501],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002244882,0.00004267938,3.83672e-7,0.0001370135,0.00003790503,0.00002268125,0.00003235501,0.4804926,0.5185227,0.0001879851,0.00003269223,0.0004685102],"study_design_scores_gemma":[0.000357087,0.0004481285,0.00003532504,0.0001907246,0.00006610877,0.000008650522,0.00000769027,0.3679066,0.63059,0.00005219833,0.0001540662,0.00018341],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9031602,0.0007832659,0.09460998,0.00003749099,0.0009470588,0.0002299366,0.00002027392,0.0001945852,0.00001718946],"genre_scores_gemma":[0.9963989,0.000009870171,0.003253677,0.000005359152,0.0002446928,0.000002160534,0.000002907051,0.00005812129,0.00002432389],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.112586,"threshold_uncertainty_score":0.999951,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01375945890791166,"score_gpt":0.226091127727822,"score_spread":0.2123316688199103,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}