{"id":"W2022370900","doi":"10.1007/s00345-004-0474-0","title":"Use of antisense oligonucleotides targeting the cytoprotective gene, clusterin, to enhance androgen- and chemo-sensitivity in prostate cancer","year":2005,"lang":"en","type":"review","venue":"World Journal of Urology","topic":"Clusterin in disease pathology","field":"Medicine","cited_by":99,"is_retracted":false,"has_abstract":false,"ca_institutions":"Vancouver General Hospital; University of British Columbia","funders":"","keywords":"Clusterin; Prostate cancer; Cancer research; Medicine; Prostate; Apoptosis; Cancer; Internal medicine; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000487131,0.0007348067,0.001138785,0.001145603,0.0002034043,0.0005599479,0.000776824,0.0006195484,0.001232787],"category_scores_gemma":[0.0003259264,0.0002483615,0.0002835193,0.001127463,0.0004082371,0.0005843435,0.0002742792,0.001133727,0.0008718395],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005218165,"about_ca_system_score_gemma":0.0004789341,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00112828,"about_ca_topic_score_gemma":0.002313086,"domain_scores_codex":[0.9998997,0.00001066574,0.00001252385,0.00002453156,0.0000421444,0.00001031017],"domain_scores_gemma":[0.9998229,0.00008174093,0.00002982965,0.000005857239,0.00004383676,0.00001591576],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001813265,0.0001926415,0.0002867228,0.006772431,0.00008361938,0.0003248906,0.00005632279,0.0005537455,0.02548862,0.001860657,0.009118901,0.9550801],"study_design_scores_gemma":[0.0001292551,0.0005823292,0.00287363,0.001237945,0.0002918144,0.00366643,0.00008250643,0.0003923423,0.02784907,0.001189834,0.9616487,0.00005605524],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001437913,0.9957628,0.0007326509,0.0001378685,0.0001842739,0.0000145512,0.00001840866,0.00001954455,0.001691974],"genre_scores_gemma":[0.004755378,0.9918899,0.0009866937,0.0002060247,0.0001104994,0.00001635134,0.00006430841,0.000003660692,0.001967278],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001232787,"threshold_uncertainty_score":0.004124045,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03776663095547137,"score_gpt":0.3554923956714176,"score_spread":0.3177257647159462,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}