{"id":"W2022458507","doi":"10.1016/j.molcel.2013.04.023","title":"MITOL Regulates Endoplasmic Reticulum-Mitochondria Contacts via Mitofusin2","year":2013,"lang":"en","type":"article","venue":"Molecular Cell","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":292,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Japan Society for the Promotion of Science; Ministry of Education, Culture, Sports, Science and Technology; Sumitomo Foundation; Naito Foundation","keywords":"MFN2; Endoplasmic reticulum; Biology; Cell biology; Mitochondrion; Ubiquitin ligase; GTPase; Ubiquitin; Inner mitochondrial membrane; Biochemistry; mitochondrial fusion; Mitochondrial DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00007937075,0.0003362178,0.000269956,0.00008253663,0.0001069988,0.00006928677,0.000295417,0.0003933596,0.0007772177],"category_scores_gemma":[0.00007731008,0.000330158,0.000227726,0.0001361604,0.0001086727,0.000008757752,0.0001386193,0.0001926594,0.00116325],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001484618,"about_ca_system_score_gemma":0.00006117342,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007917383,"about_ca_topic_score_gemma":0.00001995779,"domain_scores_codex":[0.9980597,0.0001820997,0.0003530841,0.0006888641,0.0002039366,0.0005122932],"domain_scores_gemma":[0.9986629,0.0000180503,0.0001345514,0.0007737551,0.0001695924,0.0002411444],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004698534,0.0000768062,0.0003165673,0.00001848519,0.00003377537,0.00003921808,0.00002884545,0.00004086428,0.9769361,0.00006559419,0.02182044,0.0005763382],"study_design_scores_gemma":[0.000962003,0.0002951304,0.0002398273,0.000008360585,0.00003268282,0.00007947309,0.00002914571,0.000127299,0.893384,0.0002154009,0.1042623,0.0003643257],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9590217,0.000975924,0.01576276,0.0003786022,0.001683011,0.0007921311,0.00001033924,0.0000651174,0.02131041],"genre_scores_gemma":[0.9824813,0.00006334676,0.005348548,0.001876117,0.0004526502,0.0001336617,0.0002650759,0.00007709566,0.009302218],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08355204,"threshold_uncertainty_score":0.9999151,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004330379075439792,"score_gpt":0.1935844420012879,"score_spread":0.1892540629258481,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}